Document Detail


Effect of retinopathy of prematurity on scotopic spatial summation.
MedLine Citation:
PMID:  24781938     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To evaluate scotopic retinal organization in retinopathy of prematurity (ROP) through a study of spatial summation.
METHODS: Thresholds for a range of stimulus diameters (0.4°-10°) were measured using a two alternative, spatial, forced choice psychophysical procedure. The critical diameter (DCRIT) for complete summation was estimated in subjects with a history of severe ROP (N = 7) and mild ROP (N = 17). Subjects who were born preterm and never had ROP (N = 16) and term-born subjects (N = 7) were also tested. The subjects ranged in age from 9 to 17 (median 13.5) years.
RESULTS: Critical diameter for complete spatial summation was significantly larger in ROP subjects than in subjects who never had ROP and in term-born control subjects. Critical diameter varied significantly with severity of ROP.
CONCLUSIONS: The larger DCRIT values in ROP are consistent with altered organization of the post receptor retina. This may offer the ROP retina a strategy for achieving noise reduction and good dark-adapted visual sensitivity.
Authors:
Ronald M Hansen; Jena L Tavormina; Anne Moskowitz; Anne B Fulton
Related Documents :
19872338 - Thermal increments for pulsation-frequency in "accessory hearts" of notonecta.
8679498 - Assessment of autonomic function using complex demodulation and posture entrainment tec...
23804108 - The human brain encodes event frequencies while forming subjective beliefs.
19023018 - Cardiorespiratory interactions in patients with atrial flutter.
24699928 - A comparative study for robot assisted vitreoretinal surgery: micron vs. the steady-han...
19012108 - Mismatch negativity (mmn) as an index of central auditory system plasticity.
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2014-04-29
Journal Detail:
Title:  Investigative ophthalmology & visual science     Volume:  55     ISSN:  1552-5783     ISO Abbreviation:  Invest. Ophthalmol. Vis. Sci.     Publication Date:  2014 May 
Date Detail:
Created Date:  2014-05-28     Completed Date:  2014-07-22     Revised Date:  2014-11-04    
Medline Journal Info:
Nlm Unique ID:  7703701     Medline TA:  Invest Ophthalmol Vis Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  3311-3     Citation Subset:  IM    
Copyright Information:
Copyright 2014 The Association for Research in Vision and Ophthalmology, Inc.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adolescent
Child
Dark Adaptation / physiology*
Female
Humans
Male
Photic Stimulation
Psychophysics
Retinal Rod Photoreceptor Cells / physiology*
Retinopathy of Prematurity / physiopathology*
Sensory Thresholds
Visual Perception / physiology*
Grant Support
ID/Acronym/Agency:
R01 EY-010597/EY/NEI NIH HHS
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Comparison of in vivo efficacy of different ocular lubricants in dry eye animal models.
Next Document:  Circadian and noncircadian modulation of autophagy in photoreceptors and retinal pigment epithelium.