Document Detail

Effect of Red Bull energy drink on cardiovascular and renal function.
MedLine Citation:
PMID:  19653067     Owner:  NLM     Status:  MEDLINE    
Energy drink consumption has been anecdotally linked to the development of adverse cardiovascular effects in consumers, although clinical trials to support this link are lacking. The effects of Red Bull energy drink on cardiovascular and neurologic functions were examined in college-aged students enrolled at Winona State University. In a double-blind experiment where normal calorie and low calorie Red Bull were compared to normal and low calorie placebos, no changes in overall cardiovascular function nor blood glucose (mg/dL) were recorded in any participant (n = 68) throughout a 2-h test period. However, in the second experiment, nine male and twelve female participants subjected to a cold pressor test (CPT) before and after Red Bull consumption showed a significant increase in blood sugar levels pre- and post Red Bull consumption. There was a significant increase in diastolic blood pressure of the male volunteers immediately after submersion of the hand in the 5 degrees C water for the CPT. Under the influence of Red Bull, the increase in diastolic pressure for the male participants during the CPT was negated. There were no significant changes in the blood pressure of the female participants for the CPT with or without Red Bull. Finally, the CPT was used to evaluate pain threshold and pain tolerance before and after Red Bull consumption. Red Bull consumption was associated with a significant increase in pain tolerance in all participants. These findings suggest that Red Bull consumption ameliorates changes in blood pressure during stressful experiences and increases the participants' pain tolerance.
Frances R Ragsdale; Tyler D Gronli; Narjes Batool; Nicole Haight; April Mehaffey; Erin C McMahon; Thomas W Nalli; Carla M Mannello; Crystal J Sell; Patrick J McCann; Gary M Kastello; Tisha Hooks; Ted Wilson
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Publication Detail:
Type:  Controlled Clinical Trial; Journal Article     Date:  2009-08-04
Journal Detail:
Title:  Amino acids     Volume:  38     ISSN:  1438-2199     ISO Abbreviation:  Amino Acids     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-04-07     Completed Date:  2010-07-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9200312     Medline TA:  Amino Acids     Country:  Austria    
Other Details:
Languages:  eng     Pagination:  1193-200     Citation Subset:  IM    
Department of Biology, Winona State University, Winona, MN 55987, USA.
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MeSH Terms
Adaptation, Physiological
Beverages / adverse effects*
Blood Glucose / analysis
Blood Pressure
Caffeine / adverse effects,  analysis,  metabolism
Cardiovascular Physiological Phenomena*
Central Nervous System Stimulants*
Cold Temperature / adverse effects
Dietary Carbohydrates / administration & dosage,  adverse effects,  metabolism
Dietary Supplements / adverse effects*,  toxicity*
Double-Blind Method
Heart Rate
Kidney / physiology*
Pain Measurement
Pain Threshold
Saliva / chemistry
Sex Characteristics
Stress, Physiological
Time Factors
Young Adult
Reg. No./Substance:
0/Blood Glucose; 0/Central Nervous System Stimulants; 0/Dietary Carbohydrates; 58-08-2/Caffeine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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