Document Detail


Effect of Progesterone as a Tocolytic and in Maintenance Therapy during Preterm Labor.
MedLine Citation:
PMID:  22086108     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Aims: To assess the efficacy of vaginal micronized natural progesterone as a tocolytic and in maintenance therapy during threatened preterm birth. Methods: Eighty-three women with symptoms of threatened preterm birth were either randomized to study groups receiving tocolytic treatment combined with intravaginal micronized natural progesterone (200 mg daily) or to a control group receiving only tocolysis. Results: Micronized natural progesterone treatment resulted in a prolonged latency period of 32.1 ± 17.8 versus 21.2 ± 16.3 days in the control group and heavier birth weights of 2,982.8 ± 697.8 g versus 2,585.3 ± 746.6 g. No significant differences were found between the groups in admission to the neonatal intensive care unit, stay at the neonatal intensive care unit, need for a mechanical ventilator, respiratory distress syndrome or neonatal sepsis. Conclusion: The treatment of threatened preterm birth with tocolytics combined with intravaginal micronized natural progesterone significantly prolonged pregnancy and increased birth weight. However, an improvement in adverse perinatal outcomes was not observed.
Authors:
I Arikan; A Barut; M Harma; I M Harma
Related Documents :
15185098 - Prepregnancy body mass index as an important predictor of perinatal outcomes in japanese.
2641668 - Analysis of the weights of infants of bangladeshi origin attending two clinics in tower...
24680108 - Holding the baby: early mother-infant contact after childbirth and outcomes.
1415078 - Adolescent pregnancy. gestational weight gain and maternal and infant outcomes.
8213678 - Neonatal hemochromatosis associated with maternal autoantibodies against ro/ss-a and la...
1170818 - Vinyl chloride exposure in a controlled industrial environment. a long-term mortality e...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-11-11
Journal Detail:
Title:  Gynecologic and obstetric investigation     Volume:  -     ISSN:  1423-002X     ISO Abbreviation:  -     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2011-11-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7900587     Medline TA:  Gynecol Obstet Invest     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 S. Karger AG, Basel.
Affiliation:
Department of Gynecology and Obstetrics, Faculty of Medicine, Zonguldak Karaelmas University, Zonguldak, Turkey.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Interpretation of Array Comparative Genome Hybridization Data: A Major Challenge.
Next Document:  Structure of bottle-brush brushes under good solvent conditions: a molecular dynamics study.