Document Detail


Effect of probiotic or prebiotic supplementation on antibiotic therapy in the small intestinal bacterial overgrowth: a comparative evaluation.
MedLine Citation:
PMID:  23244247     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
STATISTICS: Student's t and Fisher's exact tests. In group 1, a significant improvement was obtained in 5 out of 6 symptoms, whilst in group 2 in 4 out of 6 symptoms (nausea and number of bowel movements failed to improve). Despite we observed a trend of probiotics to be more effective than prebiotics, the difference in the percentage of improved symptoms was not significant (83,3% vs 66.6%; p= 0.57). Our preliminary data show a good outcome with sequential antibioticprobiotic/ prebiotic administration in patients with SIBO.
Authors:
Rosa Rosania; Floriana Giorgio; Mariabeatrice Principi; Annacinzia Amoruso; Rosa Monno; Alfredo Di Leo; Enzo Ierardi
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Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Current clinical pharmacology     Volume:  8     ISSN:  2212-3938     ISO Abbreviation:  Curr Clin Pharmacol     Publication Date:  2013 May 
Date Detail:
Created Date:  2013-04-18     Completed Date:  2013-10-28     Revised Date:  2014-07-31    
Medline Journal Info:
Nlm Unique ID:  101273158     Medline TA:  Curr Clin Pharmacol     Country:  United Arab Emirates    
Other Details:
Languages:  eng     Pagination:  169-72     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Anti-Bacterial Agents / administration & dosage,  therapeutic use*
Blind Loop Syndrome / diagnosis,  microbiology,  therapy*
Breath Tests / methods
Female
Follow-Up Studies
Glucose / diagnostic use
Humans
Intestine, Small / microbiology
Lactobacillus casei
Lactulose / diagnostic use
Male
Middle Aged
Oligosaccharides / administration & dosage
Prebiotics*
Probiotics / administration & dosage,  therapeutic use*
Questionnaires
Rifamycins / administration & dosage,  therapeutic use
Treatment Outcome
Young Adult
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Oligosaccharides; 0/Prebiotics; 0/Rifamycins; 4618-18-2/Lactulose; 88747-56-2/rifaximin; IY9XDZ35W2/Glucose

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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