Document Detail


The effect of posterior distraction on vertebral growth in immature pigs: an experimental simulation of growing rod technique.
MedLine Citation:
PMID:  20195208     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
STUDY DESIGN: Experimental study. OBJECTIVE: The aim of this study is to evaluate the vertebral body growth under distraction forces in immature pigs treated with growing rod (GR) technique. SUMMARY OF BACKGROUND DATA: Distraction forces applied on growth plate of appendicular skeleton stimulate longitudinal growth. However, the effect of distraction forces on axial skeletal growth has not been fully investigated yet. METHODS: Twelve 10-week-old domestic pigs were used in this experimental model to simulate GR technique. Four of them were lost during postoperative period because of deep wound infection. Cranially T12-L1 and caudally L4-L5 vertebrae were instrumented by pedicle screws bilaterally, while L2 and L3 were skipped. Distraction between pedicle screws was applied at index surgery. The rods were then lengthened twice in a month interval. All subjects were evaluated with anteroposterior and lateral spinal radiograph before surgery, after surgery, and at the final follow-up. The vertebral body heights of distracted segments (HD = L2 and L3) and control segments (HC = T9, T10 and T11) were measured. Average vertebral body heights and the increase percentage in the vertebral body heights were compared among control segments and distracted segments. RESULTS: The preoperative vertebral body height was similar in 2 groups (preHC: 10.81 mm, n = 19, preHD: 11.27 mm, n = 16, P > 0.05). At the final follow-up, the average vertebral body height in distraction group was significantly higher than the control group (postHC: 17.03 mm, postHD: 18.58 mm, P < 0.05). The increase percentage in vertebral body height was higher in distracted segments, but there was no statistically significant difference between the 2 groups. CONCLUSION: The vertebral growth continues during GR instrumentation. Distraction forces might stimulate also apophyseal growth of axial skeleton.
Authors:
Güney Yilmaz; Gazi Huri; Gökhan Demirkran; Kenan Dağloğlu; Cenk Ozkan; Ahmet Alanay; Emre Acaroglu; Muharrem Yazici
Related Documents :
9308258 - Appliance wear: the patient's point of view.
19816258 - Modified design of cupid's bow in the repair of unilateral microform cleft lip: in case...
20620828 - Stability of anterior open-bite treatment with occlusal adjustment.
17884528 - A method of treating the patient with postpubescent juvenile rheumatoid arthritis.
2461138 - An evaluation of dacron prostheses in the relief of jaundice due to malignant obstruction.
2386118 - Effect of quinidine or procainamide versus no antiarrhythmic drug on sudden cardiac dea...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Spine     Volume:  35     ISSN:  1528-1159     ISO Abbreviation:  Spine     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-04-14     Completed Date:  2010-07-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7610646     Medline TA:  Spine (Phila Pa 1976)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  730-3     Citation Subset:  IM    
Affiliation:
Department of Orthopaedics and Traumatology, Hacettepe University, Ankara, Turkey.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Bone Screws
Disease Models, Animal
Internal Fixators
Lumbar Vertebrae / growth & development,  radiography,  surgery*
Osteogenesis, Distraction / methods*
Scoliosis / radiography,  surgery
Swine
Thoracic Vertebrae / growth & development,  radiography,  surgery*
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  High Mobility Group Box 1 Is Upregulated After Spinal Cord Injury and Is Associated With Neuronal Ce...
Next Document:  DensiProbe Spine: A Novel Instrument for Intraoperative Measurement of Bone Density in Transpedicula...