Document Detail

Effect of Polymer Degree of Conversion on Streptococcus mutans Biofilms.
MedLine Citation:
PMID:  23038684     Owner:  NLM     Status:  Publisher    
Biofilm-material interactions are increasingly recognized as critical to success of some materials/devices and failure of others. We use a model system of dental monomers, salivary pellicles, and oral biofilms to demonstrate for the first time that degree of conversion of cross-linked dimethacrylate polymers alters biofilm metabolic activity. This response is due primarily to leachable release (not surface chemistry) and is complex, with no changes in some biofilm measurements (i.e., biomass), and time- and leachable-dependent responses in others (i.e., metabolic activity). These results highlight the need for considering biofilm-material interactions when designing/evaluating new materials.
Alison M Kraigsley; Kathy Tang; Katrice A Lippa; John A Howarter; Sheng Lin-Gibson; Nancy J Lin
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-5
Journal Detail:
Title:  Macromolecular bioscience     Volume:  -     ISSN:  1616-5195     ISO Abbreviation:  Macromol Biosci     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-5     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101135941     Medline TA:  Macromol Biosci     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Polymers Division, National Institute of Standards and Technology, 100 Bureau Drive, Gaithersburg, MD 20899-8543, USA.
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