Document Detail

Effect of Pinus massoniana Lamb. bark extract on lytic cycle of Epstein-Barr virus.
MedLine Citation:
PMID:  23214264     Owner:  NLM     Status:  In-Process    
Pinus massoniana bark extract (PMBE) at a concentration of 60 microg/mL or more inhibits the expression of Epstein-Barr virus (EBV) lytic proteins, such as Rta, Zta, and EA-D. EBV lytic cycle was blocked by inhibiting the transcription of immediate-early genes. The results suggest that the PMBE has anti-EBV activity. Thus, the extract is potentially useful in preventing the lytic development of EBV in vitro.
Shuxia Xu; Shimin Zhang; Xuedong Wang; Yaqian Gao; Xing Qin; Kun Wu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Indian journal of experimental biology     Volume:  50     ISSN:  0019-5189     ISO Abbreviation:  Indian J. Exp. Biol.     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-12-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0233411     Medline TA:  Indian J Exp Biol     Country:  India    
Other Details:
Languages:  eng     Pagination:  708-13     Citation Subset:  IM    
College of Life Science, Henan Agriculture University, Zhenzhou, Henan, China.
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