| Effect of parotid gland massage on parotid gland Tc-99m pertechnetate uptake. | |
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MedLine Citation:
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PMID: 22524471 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Salivary dysfunction is the most common side effect associated with (131)I therapy in patients with differentiated thyroid cancer. The purpose of this study was to evaluate the effect of parotid gland (PG) massage on radioisotope accumulation in the salivary gland. METHODS: Sixty patients were included in this study. Using Tc-99m pertechnetate, two salivary scans were performed in all patients. In 30 patients, PG massage was performed between the two salivary gland scans, whereas in the other 30 patients no massage was performed between the two scans. Total counts of both PGs and accumulation ratios were calculated. RESULTS: In the patients who received massage, no difference was observed between the mean PG counts of first and second images (8556.9±3333.4 count vs. 8598.3±3341.3 count, p=0.39). In the patients who did not receive massage, the mean PG count on second images was significantly higher than that on first images (8581.2±3618.0 count vs. 9096.4±3654.0 count, p<0.01). Mean accumulation ratio in the patients who received massage was significantly lower than in the patients who did not receive massage (0.5%±3.3% vs. 6.8%±3.8%, p<0.01). Further, among the patients who received massage there was a higher percentage of patients with a negative accumulation ratio than among the patients who did not receive massage (43.3% vs. 0%, p<0.01). CONCLUSIONS: PG massage can reduce Tc-99m pertechnetate accumulation in the PG, and thus, should be helpful to prevent salivary damage associated with (131)I therapy. |
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Authors:
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Hae Won Kim; Byeong-Cheol Ahn; Sang-Woo Lee; Jaetae Lee |
Publication Detail:
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Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't Date: 2012-04-23 |
Journal Detail:
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Title: Thyroid : official journal of the American Thyroid Association Volume: 22 ISSN: 1557-9077 ISO Abbreviation: Thyroid Publication Date: 2012 Jun |
Date Detail:
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Created Date: 2012-06-06 Completed Date: 2012-10-30 Revised Date: 2013-04-16 |
Medline Journal Info:
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Nlm Unique ID: 9104317 Medline TA: Thyroid Country: United States |
Other Details:
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Languages: eng Pagination: 611-6 Citation Subset: IM |
Affiliation:
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Department of Nuclear Medicine, Kyungpook National University School of Medicine, 50 Samduk-dong 2-ga, Daegu, South Korea . |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Female Humans Hyperthyroidism / metabolism* Iodine Radioisotopes / adverse effects, therapeutic use Male Massage* Middle Aged Parotid Gland / metabolism* Prospective Studies Radionuclide Imaging Salivary Glands / radionuclide imaging Sodium Pertechnetate Tc 99m / metabolism* Thyroid Neoplasms / radiotherapy Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Iodine Radioisotopes; 23288-60-0/Sodium Pertechnetate Tc 99m |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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