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Effect of Parotid Gland Massage on Parotid Gland Tc-99m pertechnetate Uptake.
MedLine Citation:
PMID:  22263624     Owner:  NLM     Status:  Publisher    
Background: Salivary dysfunction is the most common side effect associated with I-131 therapy in patients with differentiated thyroid cancer. The purpose of this study was to evaluate the effect of parotid gland massage on radioisotope accumulation in the salivary gland. Methods: Sixty patients were included in this study. Using Tc-99m pertechnetate, two salivary scans were performed in all patients. In 30 patients (massage groups), parotid gland massage was performed between the two salivary gland scans, whereas in the other 30 patients (no massage groups) no procedure was performed between the two scans. Total counts of both parotid glands and accumulation ratios were calculated. Results: In the massage groups, no difference was observed between the mean parotid gland counts of first and second images (8556.9 ± 3333.4 count vs. 8598.3 ± 3341.3 count, p = 0.39). In the no massage groups, the mean parotid gland count on second images was significantly higher than that on first images (8581.2 ± 3618.0 count vs. 9096.4 ± 3654.0 count, p < 0.01). Mean accumulation ratio in the massage groups was significantly lower than that in the no massage groups (0.5 ± 3.3% vs. 6.8 ± 3.8%, p < 0.01). Furthermore, the massage groups had a higher percentage of patients with a negative accumulation ratio than the no massage groups (43.3% vs. 0%, p < 0.01). Conclusions: Parotid gland massage can reduce Tc-99m pertechnetate accumulation in the parotid gland, and thus, should be helpful to prevent salivary damage associated with I-131 therapy.
Hae Won Kim; Byeong-Cheol Ahn; Sang-Woo Lee; Jaetae Lee
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-1-20
Journal Detail:
Title:  Thyroid : official journal of the American Thyroid Association     Volume:  -     ISSN:  1557-9077     ISO Abbreviation:  -     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-1-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9104317     Medline TA:  Thyroid     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Kyungpook National University School of Medicine, Department of Nuclear Medicine, Daegu, Korea, Republic of;
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