Document Detail

Effect of organic selenium supplementation on growth, Se uptake, and nutrient utilization in guinea pigs.
MedLine Citation:
PMID:  19506806     Owner:  NLM     Status:  MEDLINE    
Forty weaned male guinea pigs (Cavia porcellus) of 152.6 +/- 7.96 g mean body weight were divided into four equal groups and fed a common basal diet comprised of 25% ground cowpea (Vigna unguiculata) hay, 30% ground maize (Zea mays) grain, 22% ground gram (Cicer arietinum) grain, 9.5% deoiled rice (Oryza sativa) bran, 6% soybean (Glycine max) meal, 6% fish meal, 1.5% mineral mixture (without Se), and ascorbic acid at 200 mg/kg to meet their nutrient requirements along with 0, 0.1, 0.2, and 0.3 ppm of organic selenium (Se) in groups I, II, III, and IV, respectively. Experimental feeding lasted for a period of 10 weeks, during which, daily feed intake and weekly body weights were recorded. Intake and digestibility of dry matter, organic matter, ether extract, crude fiber, and nitrogen-free extract as well as uptake of calcium and phosphorus were similar (P > 0.05) among the four groups. Feed:gain ratio was also similar (P > 0.05) in the four groups. However, digestibility of crude protein was significantly (P < 0.001) higher in group II supplemented with 0.1 ppm organic Se as compared to other three group. Intake and absorption of Se was significantly (P < 0.001) higher in all the Se supplemented groups as compared to control group. Average daily gain (ADG) was significantly (P < 0.05) higher in group II (3.16 g/day) and III (3.38 g/day) as compared to group I (2.88 g/day). However, ADG in group IV (supplemented 0.3 ppm organic Se) was significantly (P < 0.05) lower (2.83 g/day) than group II and III, but comparable (P > 0.05) to group I. Findings of the present experiment suggests that Se requirements of guinea pigs are > or =0.2 ppm, as supplementation of 0.1 ppm organic Se in the diet (having 0.1 ppm Se) not only enhanced their growth rate but also improved the protein utilization.
Mahima Chaudhary; Anil Kumar Garg; Ganesh Kumar Mittal; Vishal Mudgal
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Publication Detail:
Type:  Journal Article     Date:  2009-06-09
Journal Detail:
Title:  Biological trace element research     Volume:  133     ISSN:  1559-0720     ISO Abbreviation:  Biol Trace Elem Res     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-02-01     Completed Date:  2010-03-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7911509     Medline TA:  Biol Trace Elem Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  217-26     Citation Subset:  IM    
Mineral and Vitamin Nutrition Laboratory, Centre of Advanced Studies in Animal Nutrition, Indian Veterinary Research Institute, Izatnagar, 243122, UP, India.
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MeSH Terms
Animal Feed* / analysis
Animal Nutritional Physiological Phenomena
Body Weight
Dietary Supplements*
Feces / chemistry
Guinea Pigs* / growth & development,  metabolism
Random Allocation
Selenium / administration & dosage,  pharmacology*
Reg. No./Substance:

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