| Effect of Microfluidization on <i>in Vitro</i> Micellization and Intestinal Cell Uptake of Lutein from <i>Chlorella vulgaris</i> | |
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MedLine Citation:
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PMID: 21776960 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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<i>Chlorella</i> is a nutrient-rich microalga that contains protein, lipid, minerals, vitamins, and high levels of lutein. This study evaluated the bioavailability of lutein from <i>Chlorella vulgaris</i> using a coupled <i>in vitro</i> digestion and human intestinal Caco-2 cell model. Lutein bioavailability was low and approximately 75% of total <i>C. vulgaris</i> lutein was not micellized during the digestion process, but remained in the insoluble digestate. Microfluidization improved lutein micellization efficiency during <i>C. vulgaris</i> digestion. <i>C. vulgaris</i> was microfluidized at a pressure exceeding 10,000 psi and the cell surface disruption was visualized by scanning electron microscopy. The mean <i>C. vulgaris</i> particle size was reduced from 3.56 to 0.35 μm with the microfluidization treatment. <i>C. vulgaris</i> microfluidization at 20,000 psi was three times more efficient for aqueous lutein micelles production compared with untreated <i>C. vulgaris</i>, and the final lutein content accumulated by intestinal Caco-2 cells was also higher with microfluidization. <i>C. vulgaris</i> lutein stability was not affected by microfluidization. These results indicate that microfluidization may be useful for improving lutein bioavailability from <i>C. vulgaris</i> during food processing. |
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Authors:
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Kwang Hyun Cha; Joo Young Lee; Dae-Geun Song; Sang Min Kim; Dong-Un Lee; Jin-Young Jeon; Cheol-Ho Pan |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-7-20 |
Journal Detail:
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Title: Journal of agricultural and food chemistry Volume: - ISSN: 1520-5118 ISO Abbreviation: - Publication Date: 2011 Jul |
Date Detail:
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Created Date: 2011-7-22 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0374755 Medline TA: J Agric Food Chem Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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