Document Detail


Effect of MR distortion on targeting for deep-brain stimulation.
MedLine Citation:
PMID:  20388592     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Deep-brain stimulation (DBS) surgery involves placing electrodes within specific deep-brain target nuclei. Surgeons employ MR imaging for preoperative selection of targets and computed tomography (CT) imaging for designing stereotactic frames used for intraoperative placement of electrodes at the targets. MR distortion may contribute to target-selection error in the MR scan and also to MR-CT registration error, each of which contributes to error in electrode placement. In this paper, we analyze the error contributed by the MR distortion to the total DBS targeting error. Distortion in conventional MR scans, both T1 and T2 weighted, were analyzed for six bilateral DBS patients in the typical areas of brain using typical scans on a 3-T clinical scanner. Mean targeting error due to MR distortion in T2 was found to be 0.07 +/- 0.025 mm with a maximum of 0.13 mm over 12 targets; error in the T1 images was smaller by 4%.
Authors:
Ramya Balachandran; E Brian Welch; Benoit M Dawant; J Michael Fitzpatrick
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2010-04-12
Journal Detail:
Title:  IEEE transactions on bio-medical engineering     Volume:  57     ISSN:  1558-2531     ISO Abbreviation:  IEEE Trans Biomed Eng     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-07-27     Completed Date:  2010-10-28     Revised Date:  2011-08-01    
Medline Journal Info:
Nlm Unique ID:  0012737     Medline TA:  IEEE Trans Biomed Eng     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1729-35     Citation Subset:  IM    
Affiliation:
Department of Otolaryngology, Vanderbilt University Medical Center, Nashville, TN 37222, USA. ramya.balachandran@vanderbilt.edu
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MeSH Terms
Descriptor/Qualifier:
Brain / anatomy & histology*
Deep Brain Stimulation*
Electrodes, Implanted
Humans
Magnetic Resonance Imaging / methods*
Signal Processing, Computer-Assisted*
Surgery, Computer-Assisted / methods*
Grant Support
ID/Acronym/Agency:
R01 EB006136/EB/NIBIB NIH HHS; R01 EB006136-04/EB/NIBIB NIH HHS; R01 EB006136-05/EB/NIBIB NIH HHS; R01 EB006136-06/EB/NIBIB NIH HHS
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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