Document Detail

Effect of HLA-compatibility in married couples on the development and severity of gestosis.
MedLine Citation:
PMID:  17970207     Owner:  NLM     Status:  MEDLINE    
We studied the effect of histocompatibility in married couples on the development and severity of gestosis. It was found that gestosis more often develops in women with two common HLA alleles of class II major histocompatibility complex with her husband. The greatest number of coincidences was detected in subgroups with medium and severe gestosis. Perinatal outcomes in women with medium-severe gestosis having HLA-alleles common with husbands are characterized by delivery of babies with lower body weight.
G T Sukhikh; R A Nurutdinova; L E Murashko; L Z Faizullin
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Bulletin of experimental biology and medicine     Volume:  143     ISSN:  0007-4888     ISO Abbreviation:  Bull. Exp. Biol. Med.     Publication Date:  2007 Feb 
Date Detail:
Created Date:  2007-10-31     Completed Date:  2008-01-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372557     Medline TA:  Bull Exp Biol Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  222-4     Citation Subset:  IM    
Research Center of Obstetrics, Gynecology, and Perinatology, Russian Academy of Medical Sciences, Moscow.
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MeSH Terms
Birth Weight / genetics
Gene Frequency
HLA Antigens / genetics*
Histocompatibility Testing / methods*
Infant, Newborn
Pregnancy Complications / genetics*
Reg. No./Substance:
0/HLA Antigens

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