Document Detail

Effect of HIV-2 Infection on HIV-1 Disease Progression.
MedLine Citation:
PMID:  23150973     Owner:  NLM     Status:  In-Data-Review    
To the Editor: Esbjörnsson and colleagues (July 19 issue)(1) conclude that infection with human immunodeficiency virus type 2 (HIV-2) attenuates the course of HIV-1 infection. Their report raises three issues. First, in Guinea-Bissau, up to 30% of persons infected with both HIV-1 and HIV-2 have coinfection with human T-cell lymphotropic virus type 1 (HTLV-1),(2) a circumstance that leads to an increased percentage of CD4+ T cells.(3) The authors did not control for coinfection with HTLV-1, a condition that may well have contributed to the high percentage of CD4+ T cells among persons with dual HIV infection. Second, despite the study's . . .
Carla van Tienen; Maarten Schim van der Loeff; Hilton Whittle
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The New England journal of medicine     Volume:  367     ISSN:  1533-4406     ISO Abbreviation:  N. Engl. J. Med.     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0255562     Medline TA:  N Engl J Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1961-3     Citation Subset:  AIM; IM    
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