Document Detail

Effect of gentamicin-absorbed collagen in wound healing in pilonidal sinus surgery: a prospective randomized study.
MedLine Citation:
PMID:  20819439     Owner:  NLM     Status:  MEDLINE    
Pilonidal sinus is a common disease that causes the loss of many working hours, but treatment is variable and problematic. The effect of gentamicin-absorbed collagen on healing, infection and recurrence, and length of hospital stay were examined after pilonidal sinus surgery. Patients undergoing surgical treatment for pilonidal sinus were randomly assigned into two groups each of 40 patients. Both groups were treated with excision and primary closure under local anaesthesia. Group 1 (control) received oral antibiotics for 7 days post-operatively. In group 2, prior to wound closure, gentamicin-absorbed collagen sponges were placed on the sacral fascia and these patients did not receive oral post-operative antibiotic therapy. Patients in group 2 had a significantly shorter mean wound healing time, significantly lower infection and recurrence rates, and a significantly shorter hospital stay than those in group 1. It is concluded that implantation of a gentamicin-containing collagen sponge on the wound area in pilonidal sinus decreased the rates of infection and recurrence, and shortened the hospital stay.
I Yetim; O V Ozkan; A Dervişoglu; K Erzurumlu; E Canbolant
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  The Journal of international medical research     Volume:  38     ISSN:  0300-0605     ISO Abbreviation:  J. Int. Med. Res.     Publication Date:    2010 May-Jun
Date Detail:
Created Date:  2010-09-07     Completed Date:  2010-09-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0346411     Medline TA:  J Int Med Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  1029-33     Citation Subset:  IM    
Department of General Surgery, Mustafa Kemal University Medical Faculty, Antakya-Hatay, Turkey.
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MeSH Terms
Administration, Oral
Administration, Topical
Anti-Bacterial Agents / administration & dosage*
Drug Implants
Gentamicins / administration & dosage*
Length of Stay
Pilonidal Sinus / drug therapy*,  pathology,  surgery
Prospective Studies
Surgical Sponges*
Surgical Wound Infection / prevention & control
Treatment Outcome
Wound Healing
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Drug Implants; 0/Gentamicins; 9007-34-5/Collagen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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