Document Detail


Effect of Galla chinensis on enhancing remineralization of enamel crystals.
MedLine Citation:
PMID:  19498222     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The aim of this scanning electron microscopy (SEM) study was to investigate the effect of chemical compounds of Galla chinensis (GCE, gallic acid) on the remineralization of enamel crystals in vitro. Bovine enamel blocks with an in vitro produced initial lesion were used. The lesions were subjected to a pH-cycling regime for 12 days. Each daily cycle included 4 x 1 min applications with one of six treatments: group A: 1000 ppm F aq. (as NaF, positive control); group B: deionized water (DDW, negative control); group C: 4000 ppm crude aqueous extract of GCE; group D: 4000 ppm gallic acid; group E: 4000 ppm GCE with 1000 ppm F; group F: 4000 ppm gallic acid with 1000 ppm F. The surface and vertical section of the enamel lesions were analyzed by SEM. The results indicated that the chemical compounds of G. chinensis could regulate the de-/remineralization balance through influencing the morphology and structure of enamel crystals, and the mechanisms seem to be different for GCE and gallic acid.
Authors:
Lei Cheng; Ji Yao Li; Shengbin Huang; Xue Dong Zhou
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-06-05
Journal Detail:
Title:  Biomedical materials (Bristol, England)     Volume:  4     ISSN:  1748-605X     ISO Abbreviation:  Biomed Mater     Publication Date:  2009 Jun 
Date Detail:
Created Date:  2009-06-05     Completed Date:  2009-08-20     Revised Date:  2010-03-11    
Medline Journal Info:
Nlm Unique ID:  101285195     Medline TA:  Biomed Mater     Country:  England    
Other Details:
Languages:  eng     Pagination:  034103     Citation Subset:  IM    
Affiliation:
State Key Laboratory of Oral Disease, Sichuan University, Chengdu, People's Republic of China. stonedentist@yahoo.cn
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MeSH Terms
Descriptor/Qualifier:
Animals
Bone Matrix / drug effects*
Calcification, Physiologic / drug effects*
Cattle
Crystallization / methods
Dental Caries / drug therapy*,  physiopathology*
Dental Enamel / drug effects*
Drugs, Chinese Herbal / pharmacology*
Feasibility Studies
Chemical
Reg. No./Substance:
0/Drugs, Chinese Herbal

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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