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Effect of Exercise Modality and Intensity on Post-Exercise Interleukin-6 and Hepcidin Levels.
MedLine Citation:
PMID:  23070801     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The effect of exercise modality and intensity on interleukin-6 (IL-6), iron status and hepcidin levels was investigated. Ten trained male triathletes performed four exercise trials, including; (a) low intensity continuous running (L-R); (b) low intensity continuous cycling (L-C); (c) high intensity interval running (H-R); and (d) high intensity interval cycling (H-C). Both L-R and L-C consisted of 40 min continuous exercise performed at 65% of peak running velocity (vVO2peak) and cycling power output (pVO2peak), while H-R and H-C consisted of 8 x 3 min intervals performed at 85% vVO2peak and pVO2peak. Venous blood samples were drawn pre-, post- and 3 h post-exercise. Significant increases in post-exercise IL-6 were seen within each trial (p<0.05), and were significantly greater in H-R than L-R (p<0.05). Hepcidin levels were significantly elevated at 3 h post-exercise within each trial (p<0.05). Serum iron levels were significantly elevated (p<0.05) immediately post-exercise in all trials except L-C. These results suggest that, regardless of exercise mode or intensity, post-exercise increases in IL-6 may be expected, likely influencing a subsequent elevation in hepcidin. Regardless, the lack of change in post-exercise serum iron levels in L-C may indicate that reduced hemolysis occurs during weight supported, low intensity activity.
Authors:
Marc Sim; Brian Dawson; Grant Landers; Dorine W Swinkels; Harold Tjalsma; Debbie Trinder; Peter Peeling
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-11
Journal Detail:
Title:  International journal of sport nutrition and exercise metabolism     Volume:  -     ISSN:  1543-2742     ISO Abbreviation:  Int J Sport Nutr Exerc Metab     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100939812     Medline TA:  Int J Sport Nutr Exerc Metab     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
School of Sport Science, Exercise and Health, The University of Western Australia, Crawley, Western Australia, Australia.
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