Document Detail

The Effect of Exclusive Breastfeeding on Respiratory Illness in Young Infants in a Maternal Immunization Trial in Bangladesh.
MedLine Citation:
PMID:  23249922     Owner:  NLM     Status:  Publisher    
BACKGROUND:: Exclusive breastfeeding reduces the risk of respiratory illness in infants younger than 6 months of age in developing countries by approximately half. We evaluated the effect of exclusive breastfeeding on respiratory illness with fever (RIF) in Bangladeshi infants in the context of a randomized maternal influenza immunization trial. METHODS:: Infants in a maternal vaccine trial in Dhaka, Bangladesh were prospectively assessed at weekly intervals for 6 months after birth for breastfeeding practices and RIF. We estimated the risk of a RIF episode for infants who were exclusively breastfed the prior week compared with infants not exclusively breastfed the prior week using generalized estimating equations. RESULTS:: We followed a total of 331 infants from birth to 24 weeks of age. The median weeks infants were exclusively breastfed was 15 (IQR 6-21). The adjusted independent odds of respiratory illness for exclusively breastfed infants compared with non-exclusively breastfed infants was 0.59 (95% CI 0.45-0.77) for a RIF episode. After adjusting for exclusive breastfeeding, we confirmed the previous report that maternal immunization with influenza vaccine had an independent protective effect against RIF (OR 0.72, 95% CI 0.55-0.93). No significant difference in the protective effect of exclusive breastfeeding was seen by maternal influenza immunization status. CONCLUSIONS:: Exclusive breastfeeding during the first 6 months of life and maternal immunization with influenza vaccine independently and substantially reduced respiratory illness with fever in infants.
Emily Henkle; Mark C Steinhoff; Saad B Omer; Eliza Roy; Shams E Arifeen; Rubhana Raqib; Robert F Breiman; Laura E Caulfield; William J Moss; Khalequ Zaman
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-12-17
Journal Detail:
Title:  The Pediatric infectious disease journal     Volume:  -     ISSN:  1532-0987     ISO Abbreviation:  Pediatr. Infect. Dis. J.     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8701858     Medline TA:  Pediatr Infect Dis J     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
1Center for Health Research-Northwest, Kaiser Permanente, Portland, OR, USA 2Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA 3Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA 4Rollins School of Public Health, Emory University, Atlanta, GA, USA 5Center for Health Research-Southeast, Kaiser Permanente, Atlanta, GA, USA 6ICDDR,B, Dhaka, Bangladesh.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Comparative Analysis of Pediatric and Adult Visceral Leishmaniasis in Brazil.
Next Document:  Generation of 6H-benzo[f]cyclopenta[d][1,2]thiazepine 5,5-dioxides via a palladium-catalyzed reactio...