| Effect of endurance exercise training on oxidative stress in spontaneously hypertensive rats (SHR) after emergence of hypertension. | |
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MedLine Citation:
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PMID: 20828222 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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The purpose of this study is to elucidate the effect of wheel training on oxidative stress maker levels in spontaneous hypertensive rats (SHR). 4-hydroxynonenal and 3-nitrotyrosine levels in the aorta of SHRs were allowed to run for 10 weeks from the age of 15 weeks were measured and compared with those of nonexercised SHRs. The 4-hydroxynonenal and 3-nitrotyrosine levels in the exercised group were significantly lower than those in the nonexercised group. The exercised group showed a significant increase of manganese-containing superoxide dismutase. Endurance exercise showed a possible suppressing effect on the arteriosclerosis development by reducing oxidative stress, even after emergence of hypertension. |
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Authors:
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Hiroko Kimura; Nobuko Kon; Satoshi Furukawa; Masahiro Mukaida; Fumiyuki Yamakura; Kazuko Matsumoto; Hirohito Sone; Kimiko Murakami-Murofushi |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-09-09 |
Journal Detail:
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Title: Clinical and experimental hypertension (New York, N.Y. : 1993) Volume: 32 ISSN: 1525-6006 ISO Abbreviation: Clin. Exp. Hypertens. Publication Date: 2010 |
Date Detail:
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Created Date: 2010-10-29 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9305929 Medline TA: Clin Exp Hypertens Country: England |
Other Details:
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Languages: eng Pagination: 407-15 Citation Subset: IM |
Affiliation:
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Department of Forensic Medicine, Juntendo University School of Medicine, Tokyo, Japan. hkim@juntendo.ac.jp |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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