| Effect of E. coli endotoxin on temperature, oxygen consumption and brown adipose tissue thermogenesis in rats and mice. | |
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MedLine Citation:
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PMID: 3322420 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The effects of E. coli endotoxin 0127 B8 on oxygen consumption, temperature, and on the activity of the proton conductance pathway in brown adipose tissue (BAT) were investigated in rats and mice. In rats an increase was observed in rectal and skin temperature, whole body oxygen consumption and GDP binding in BAT. In mice only the rise in rectal and skin temperature were significantly changed by endotoxin administration. These findings suggest that in some species BAT is involved in the production of endotoxin induced fever and increased energy expenditure. |
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Authors:
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G Jennings; M Elia |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Bioscience reports Volume: 7 ISSN: 0144-8463 ISO Abbreviation: Biosci. Rep. Publication Date: 1987 Jun |
Date Detail:
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Created Date: 1988-03-14 Completed Date: 1988-03-14 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8102797 Medline TA: Biosci Rep Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 517-23 Citation Subset: IM |
Affiliation:
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Dunn Nutrition Laboratory, Cambridge. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adipose Tissue, Brown
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drug effects* Animals Body Temperature Regulation / drug effects* Endotoxins / toxicity* Escherichia coli Male Mice Oxygen Consumption / drug effects* Rats |
| Chemical | |
Reg. No./Substance:
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0/Endotoxins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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