Document Detail


Effect of Disc Degeneration on Lumbar Segmental Mobility analyzed by Kinetic Magnetic Resonance Imaging.
MedLine Citation:
PMID:  25494318     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Study Design. Retrospective radiographic study.Objective. To define the relationship between the grade of disc degeneration and the motion of the lumbar spine by using kinetic MRI.Summary of Background Data. Disc degeneration is common after middle age. Lumbar instability has generally been recognized as a potential risk factor of low back pain. However, correlations between the grade of disc degeneration and the motion of the lumbar spine need more investigation.Methods. Kinetic MRI was performed in 162 patients with symptomatic low back pain without prior history of surgery. The lumbar intervertebral discs were graded by spine surgeons according to the degenerative grading system (Grades I to V). Translational motion and angular variation were measured at each segment from L1-L2 through L5-S1. The relationship between the degree of lumbar disc degeneration and extent of lumbar spine mobility was analyzed.Results. The translational motion in discs with Grade I through IV increased gradually, but decreased with Grade V. Compared to other less degenerative grades, Grade V discs had significantly decreased total intervertebral translational motion (P < 0.05). The angular variation in discs with Grade I through IV was fairly constant, but decreased with Grade V. Compared to other degenerative grades (I-IV), Grade V discs had significantly decreased total intervertebral translational motion (P < 0.05). For less degenerative Grades I and II discs, the L2-L3 and L3-L4 segmental units contributed the majority of total angular mobility of the spine. However, for the severely degenerated segments, Grade V discs, the contributions of the L2-L3 and L3-L4 significantly decreased (P < 0.01).Conclusions. As disc degeneration developed from the normal to an increasingly severe stage, the motion of lumbar spine progressed from the normal stage to an unstable phase with higher mobility and finally to an ankylosed stage where stability was increased.
Authors:
Lifeng Lao; Michael D Daubs; Trevor P Scott; Elizabeth L Lord; Jeremiah R Cohen; Ruofeng Yin; Guibin Zhong; Jeffrey C Wang
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-12-9
Journal Detail:
Title:  Spine     Volume:  -     ISSN:  1528-1159     ISO Abbreviation:  Spine     Publication Date:  2014 Dec 
Date Detail:
Created Date:  2014-12-10     Completed Date:  -     Revised Date:  2014-12-11    
Medline Journal Info:
Nlm Unique ID:  7610646     Medline TA:  Spine (Phila Pa 1976)     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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