| Effect of D- and/or L-aspartic acids on feeding, drinking, urine outflow and core temperature. | |
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MedLine Citation:
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PMID: 7163357 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Rats were given D- and/or L-aspartic acids (Asp) in saccharin solution for one week. Body weight gain, daily food and fluid intake, weight of faeces, urine outflow and osmolality, and rectal temperature were compared with those of the pretreatment period. After the rats had been sacrificed the weights of liver, spleen and kidney were estimated and compared with those of the control. The long-term oral administration of D-Asp caused a significant decrease in the weights of total body, liver and kidney, in the daily food and fluid intake, in the weight of faeces and in the volume of urine. The osmolality of urine of the rats administered D-Asp was significantly higher than that of the control. The concomitant oral administration of L-Asp seemed to antagonize the effects of D-Asp. |
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Authors:
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H Koyuncuoğlu; K Berkman |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Pharmacology, biochemistry, and behavior Volume: 17 ISSN: 0091-3057 ISO Abbreviation: Pharmacol. Biochem. Behav. Publication Date: 1982 Dec |
Date Detail:
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Created Date: 1983-04-21 Completed Date: 1983-04-21 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0367050 Medline TA: Pharmacol Biochem Behav Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1265-9 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Aspartic Acid / pharmacology* Body Temperature Regulation / drug effects* Body Weight / drug effects Diuresis / drug effects* Drinking / drug effects* Eating / drug effects* Kidney / drug effects Liver / drug effects Male Organ Size / drug effects Rats Rats, Inbred Strains Spleen / drug effects Stereoisomerism Water-Electrolyte Balance / drug effects |
| Chemical | |
Reg. No./Substance:
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56-84-8/Aspartic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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