| Effect of cibenzoline on biventricular pressure gradients in a pediatric patient with hypertrophic obstructive cardiomyopathy. | |
| | |
MedLine Citation:
|
PMID: 20140606 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
This report presents the case of an 8-year-old male with biventricular hypertrophic obstructive cardiomyopathy who achieved a successful reduction of the pressure gradients by treatment with cibenzoline. Ultrasound echocardiography showed marked intraventricular septal hypertrophy and left midventricular and right ventricular outflow obstructions. A cardiac catheterization revealed left midventricular and right outflow obstructions associated with pressure gradients of 100 and 35 mmHg, respectively. An intravenous injection of 28 mg (1.4 mg/kg) cibenzoline immediately improved the biventricular pressure gradients. Therefore, oral cibenzoline treatment was initiated, the dose was increased to 150 mg/day, and both pressure gradients remained low, without any complications at the time of discharge, 4 months later. |
| | |
Authors:
|
Takamichi Ishikawa; Satoru Iwashima; Takehiko Ohzeki |
Related Documents
:
|
2208256 - Simplified method for estimating true aortic valve mean gradient from simultaneous left... 2026816 - Calculation of pressure gradients from mr velocity data in a laminar flow model. 5129316 - Pressure-flow studies in man: effect of atrial systole on ventricular function in mitra... 20828746 - Continuous-flow cardiac assistance: effects on aortic valve function in a mock loop. 12873126 - Volume and compressibility changes accompanying thermally-induced native-to-unfolded an... 15313496 - Physiological thermoregulation in a crustacean? heart rate hysteresis in the freshwater... |
Publication Detail:
|
Type: Case Reports; Journal Article Date: 2010-02-07 |
Journal Detail:
|
Title: Pediatric cardiology Volume: 31 ISSN: 1432-1971 ISO Abbreviation: Pediatr Cardiol Publication Date: 2010 Jul |
Date Detail:
|
Created Date: 2010-06-17 Completed Date: 2010-10-14 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8003849 Medline TA: Pediatr Cardiol Country: United States |
Other Details:
|
Languages: eng Pagination: 707-10 Citation Subset: IM |
Affiliation:
|
Department of Pediatrics, Hamamatsu University School of Medicine, Higashi-ku, Hamamatsu, Japan. takamichinet@aol.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Anti-Arrhythmia Agents
/
administration & dosage,
therapeutic use* Cardiomyopathy, Hypertrophic / drug therapy*, physiopathology, ultrasonography Child Echocardiography Heart Catheterization Humans Imidazoles / administration & dosage, therapeutic use* Male Ventricular Outflow Obstruction / drug therapy*, physiopathology, ultrasonography |
| Chemical | |
Reg. No./Substance:
|
0/Anti-Arrhythmia Agents; 0/Imidazoles; 53267-01-9/cifenline |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Fetoscopic Fetal Transesophageal Electrocardiography: A Minimally Invasive Tool for Cardiac Monitori...
Next Document: MicroRNAs in cardiac development.