| Effect of CaF2 on densification and properties of hydroxyapatite-zirconia composites for biomedical applications. | |
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MedLine Citation:
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PMID: 12182313 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Hydroxyapatite (HA) composites with zirconia (ZrO2) up to 40 vol% were fabricated with the addition of CaF2. The sinterability of the composites was found to be enhanced markedly by the addition of small amounts of CaF2 (< 5 vol%). Decomposition of HA to beta-TCP was suppressed due to the substitution of F- for OH-, consequently forming fluor-hydroxyapatite (FHA) solid solution. This suppression of decomposition allowed the production of a fully dense body, which retained both high flexural strength and fracture toughness. The osteoblast-like cell (MG63) response to these F- ion-containing composites displayed comparable cell viability to pure-HA by in vitro proliferation test. |
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Authors:
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Hae-Won Kim; Yoon-Jung Noh; Young-Hag Koh; Hyoun-Ee Kim; Hyun-Man Kim |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Biomaterials Volume: 23 ISSN: 0142-9612 ISO Abbreviation: Biomaterials Publication Date: 2002 Oct |
Date Detail:
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Created Date: 2002-08-16 Completed Date: 2003-01-16 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8100316 Medline TA: Biomaterials Country: England |
Other Details:
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Languages: eng Pagination: 4113-21 Citation Subset: IM |
Affiliation:
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School of Materials Science and Engineering, Seoul National University, South Korea. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Biocompatible Materials* Calcium Fluoride / chemistry* Cell Division Cell Line Durapatite / chemistry* Materials Testing Microscopy, Electron, Scanning Osteoblasts / cytology Zirconium / chemistry* |
| Chemical | |
Reg. No./Substance:
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0/Biocompatible Materials; 1306-06-5/Durapatite; 1314-23-4/zirconium oxide; 7440-67-7/Zirconium; 7789-75-5/Calcium Fluoride |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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