Document Detail


Effect of Brown Seaweed Lipids on Fatty Acid Composition and Lipid Hydroperoxide Levels of Mouse Liver.
MedLine Citation:
PMID:  21405010     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Brown seaweed lipids from <i>Undaria pinnatifida</i> (Wakame), <i>Sargassum horneri</i> (Akamoku), and <i>Cystoseira hakodatensis</i> (Uganomoku) contained several bio-active compounds, namely fucoxanthin, polyphenols, and omega-3 polyunsaturated fatty acids (PUFA). Fucoxanthin and polyphenol contents of Akamoku and Uganomoku lipids were higher than those of Wakame lipids, while Wakame lipids showed the higher total omega-3 PUFA content than Akamoku and Uganomoku lipids. The levels of docosahexaenoic acid (DHA) and arachidonic acid (AA) in liver lipids of KK-Ay mouse significantly increased by Akamoku and Uganomoku lipids feeding as compared with the control, but not by Wakame lipids feeding. Fucoxanthin has been reported to accelerate the bioconversion of omega-3 PUFA and omega-6 PUFA to DHA and AA, respectively. The higher hepatic DHA and AA level of mice fed Akamoku and Uganomoku lipids would be attributed to the higher content of fucoxanthin of Akamoku and Uganomoku lipids. The lipid hydroperoxide levels of the liver of mice fed brown seaweed lipids were significantly lower than that of control mice, even though total PUFA content was higher in the liver of mouse fed brown seaweed lipids. This would be, at least in part, due to the antioxidant activity of fucoxanthin metabolites in the liver.
Authors:
M K Widjaja-Adhi Airanthi; Naoya Sasaki; Sayaka Iwasaki; Nobuko Baba; Masayuki Abe; Masashi Hosokawa; Kazuo Miyashita
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-3-15
Journal Detail:
Title:  Journal of agricultural and food chemistry     Volume:  -     ISSN:  1520-5118     ISO Abbreviation:  -     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-3-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0374755     Medline TA:  J Agric Food Chem     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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