Document Detail


Effect of Body Position on Ventilation Distribution in Ventilated Preterm Infants.
MedLine Citation:
PMID:  23314179     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
RATIONALE:: Positioning is considered vital to the maintenance of good lung ventilation by optimizing oxygen transport and gas exchange in ventilated premature infants. Previous studies suggest that the prone position is advantageous; however, no data exist on regional ventilation distribution for this age group. OBJECTIVES:: To investigate the effect of body position on regional ventilation distribution in ventilated and nonventilated preterm infants using electrical impedance tomography. DESIGN:: Randomized crossover study design. SETTING:: Neonatal ICU. PATIENTS:: A total of 24 ventilated preterm infants were compared with six spontaneously breathing preterm infants. INTERVENTIONS:: Random assignment of the order of the positions supine, prone, and quarter prone. MEASUREMENTS AND MAIN RESULTS:: Ventilation distribution was measured with regional impedance amplitudes and global inhomogeneity indices using electrical impedance tomography. In the spontaneously breathing infants, regional impedance amplitudes were increased in the posterior compared with the anterior lung (p < 0.01) and in the right compared with the left lung (p = 0.03). No differences were found in the ventilated infants. Ventilation was more inhomogeneous in the ventilated compared with the healthy infants (p < 0.01). Assessment of temporal regional lung filling showed that the posterior lung filled earlier than the anterior lung in the spontaneously breathing infants (p < 0.02) whereas in the in the ventilated infants the right lung filled before the left lung (p < 0.01). CONCLUSIONS:: In contrast to previous studies showing that ventilation is distributed to the nondependent lung in infants and children, this study shows that gravity has little effect on regional ventilation distribution.
Authors:
Judith L Hough; Leanne Johnston; Sandy Brauer; Paul Woodgate; Andreas Schibler
Related Documents :
24951079 - Transcutaneous bilirubinometry is not influenced by term or skin color in neonates.
9713029 - Randomised controlled trial of l-carnitine as a nutritional supplement in preterm infants.
23943189 - Postnatal phenobarbital for the prevention of intraventricular haemorrhage in preterm i...
7136619 - Effects of injected lipid emulsion on oxygen consumption, rq, triglyceride, free-fatty-...
15810799 - Prevalence of aflatoxins in blood and urine of egyptian infants with protein-energy mal...
7794709 - Mineral excretion following furosemide compared with bumetanide therapy in premature in...
6461589 - Pitfalls in the etiological diagnosis of congenital adrenal hyperplasia in the early ne...
11511979 - Acute peritoneal dialysis as both cause and treatment of hypernatremia in an infant.
3899339 - Gastrointestinal peptides and the adaptation to extrauterine nutrition.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-9
Journal Detail:
Title:  Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies     Volume:  -     ISSN:  1529-7535     ISO Abbreviation:  Pediatr Crit Care Med     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100954653     Medline TA:  Pediatr Crit Care Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
1 Critical Care of the Newborn Program, Mater Medical Research Institute, South Brisbane, QLD, Australia. 2 School of Physiotherapy, Australian Catholic University, Banyo, QLD, Australia. 3 Department of Physiotherapy, Mater Health Services, South Brisbane, QLD, Australia. 4 Paediatric Critical Care Research Group (JLH, AS), Mater Health Services, South Brisbane, QLD, Australia. 5 School of Health and Rehabilitation Sciences, University of Queensland, St Lucia, QLD, Australia. 6 Department of Neonatology, Mater Mothers Hospital, South Brisbane, QLD, Australia. 7 School of Medicine, Griffith University, Gold Coast, QLD, Australia.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Global transcriptional profiling of the postmortem brain of a patient with G114V genetic Creutzfeldt...
Next Document:  Diagnostic Performance of Triggering Receptor Expressed on Myeloid Cells-1 and CD64 Index as Markers...