Document Detail


Effect of Body Mass Index on Short- and Long-term Outcomes After Transcatheter Aortic Valve Implantation.
MedLine Citation:
PMID:  23102879     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Better outcomes have been reported after percutaneous cardiac intervention in obese patients ("obesity paradox"). However, limited information is available on the effect of the body mass index on the outcomes after transcatheter aortic valve implantation (TAVI). We, therefore, sought to determine the effect of the body mass index on the short- and long-term outcomes in patients who underwent TAVI. The population consisted of 940 patients, of whom 25 (2.7%) were underweight, 384 had a (40.9%) normal weight, 372 (39.6%) were overweight, and 159 (16.9%) were obese. Overall, the obese patients were younger (79.7 ± 6.4 years vs 81.7 ± 7.3 and 80.8 ± 7.0 years, p = 0.008) and had a greater prevalence of preserved left ventricular and renal function. On univariate analysis, obese patients had a greater incidence of minor stroke (1.3% vs 0 and 0.3%, p = 0.03), minor vascular complications (15.7% vs 9.1% and 11.6%, p = 0.028) and acute kidney injury stage I (23.3% vs 10.7% and 16.1%, p <0.001). After adjustment, body mass index, as a continuous variable, was associated with a lower risk of mortality at 30 days (odds ratio 0.93, 95% confidence interval 0.86 to 0.98, p = 0.023) and no effect on survival after discharge (hazard ratio 1.01, 95% confidence interval 0.96 to 1.07, p = 0.73). In conclusion, obesity was associated with a greater incidence of minor, but no major, perioperative complications after TAVI. After adjustment, obesity was associated with a lower risk of 30-day mortality and had no adverse effect on mortality after discharge, underscoring the "obesity paradox" in patients undergoing TAVI.
Authors:
Robert M A van der Boon; Alaide Chieffo; Nicolas Dumonteil; Didier Tchetche; Nicolas M Van Mieghem; Gill L Buchanan; Olivier Vahdat; Bertrand Marcheix; Patrick W Serruys; Jean Fajadet; Antonio Colombo; Didier Carrié; Ron T van Domburg; Peter P T de Jaegere;
Related Documents :
23106799 - The impact of body mass index on surgical outcomes of robotic partial nephrectomy.
23359399 - Obesity and operative time in primary total joint arthroplasty.
10527439 - The impact of an occluded internal carotid artery on the mortality and morbidity of pat...
466329 - Comparative trial of volunteer and professional treatments of dysphasia after stroke.
24723019 - Outcome of sleeve gastrectomy as a primary bariatric procedure.
20851629 - Assessment of long-term outcomes for the stroke doc telemedicine trial.
17670009 - Endogenously acquired deep sternal wound infection after congenital cardiac surgery.
21738289 - The ambulatory closure device percutaneous intervention (abcd-pci) study: a single-cent...
15745109 - A randomized controlled trial of beta-blockers versus endoscopic band ligation for prim...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-24
Journal Detail:
Title:  The American journal of cardiology     Volume:  -     ISSN:  1879-1913     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
Affiliation:
Department of Interventional Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Utility of Combination of Cardiac Magnetic Resonance Imaging and High-Sensitivity Cardiac Troponin T...
Next Document:  Mean platelet volume and long-term mortality in patients undergoing percutaneous coronary interventi...