| Effect of bioactive glasses on angiogenesis: a review of in vitro and in vivo evidences. | |
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MedLine Citation:
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PMID: 19831556 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The incorporation of bioactive glass into bone tissue-engineered scaffolds can be widely beneficial based on emerging evidence in the literature about the angiogenic potential of this material, particularly 45S5 Bioglass((R)). This article reviews the literature discussing in vitro studies which have demonstrated that increases in angiogenic indicators have been achieved through both direct and indirect contact of relevant cells with 45S5 Bioglass((R)) particles or with their dissolution products. A few available in vivo studies confirming the ability of bioactive glass, incorporated into scaffolds, to stimulate neovascularization are also discussed. Suggestions for further research are given, highlighting the need for specific investigations designed to assess the effect of particular ion dissolution products from bioactive glasses and their relative concentration on angiogenesis both in vitro and in vivo. |
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Authors:
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Alejandro A Gorustovich; Judith A Roether; Aldo R Boccaccini |
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Publication Detail:
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Type: Evaluation Studies; Journal Article; Review |
Journal Detail:
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Title: Tissue engineering. Part B, Reviews Volume: 16 ISSN: 1937-3376 ISO Abbreviation: Tissue Eng Part B Rev Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-04-06 Completed Date: 2010-06-17 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101466660 Medline TA: Tissue Eng Part B Rev Country: United States |
Other Details:
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Languages: eng Pagination: 199-207 Citation Subset: IM |
Affiliation:
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Research Laboratory, National Atomic Energy Commission (CNEA-Reg. Noroeste), Salta, Argentina. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Angiogenesis Inducing Agents
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metabolism Animals Biocompatible Materials / pharmacology Cell Proliferation / drug effects Cells, Cultured Ceramics / pharmacology* Endothelial Cells / drug effects, metabolism, physiology Fibroblasts / drug effects, metabolism, physiology Humans Models, Animal Neovascularization, Physiologic / drug effects*, physiology |
| Chemical | |
Reg. No./Substance:
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0/Angiogenesis Inducing Agents; 0/Biocompatible Materials; 0/Bioglass; 0/Ceramics |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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