| Effect of beam hardening on arterial enhancement in thoracoabdominal CT angiography with increasing patient size: an in vitro and in vivo study. | |
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MedLine Citation:
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PMID: 20656839 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To assess the effect of beam hardening on arterial enhancement in thoracoabdominal computed tomographic (CT) angiography in various body sizes in a phantom and in a clinical study. MATERIALS AND METHODS: An abdominal aortic phantom was placed in three cylindrical water containers simulating a small, an intermediate, and a large patient (diameters of 22, 30, and 40 cm, respectively). CT scanning was performed at 80, 100, and 120 kVp, and aortic attenuation was assessed. In a HIPAA-compliant institutional review board-approved study with waiver of informed consent, thoracoabdominal aortic attenuation was assessed in 100 consecutive patients (75 men, 25 women; mean body weight (BW), 79 kg) undergoing thoracoabdominal 64-section CT angiography at 80 kVp. Overall aortic attenuation in patients grouped according to BW (small patients [n = 26], <70 kg; intermediate patients [n = 41], 70-85 kg; large patients [n = 33], >85 kg) was compared. Overall aortic attenuation was correlated with BW, height, body mass index (BMI), body surface area (BSA), and lateral diameter by using linear regression. RESULTS: Comparison of the intermediate- and large-phantom groups relative to the small-phantom group indicated that mean aortic attenuation decreased by 9.7% and 13.4% at 80 kVp, 9.8% and 15.1% at 100 kVp, and 13.8% and 23.8% at 120 kVp, respectively (P < .001). In the clinical study, the overall aortic attenuation decreased by 11.3% and 20.0% in the intermediate- and large-patient groups relative to the small-patient group, respectively (P < .05). Overall aortic attenuation correlated well with BSA (R = -0.454), height (R = -0.421), and BW (R = -0.414), followed by lateral diameter (R = -0.291) and BMI (R = -0.211). CONCLUSION: Beam hardening may substantially contribute to reduced arterial enhancement in larger patients undergoing thoracoabdominal CT angiography. The beam-hardening effect on arterial enhancement is more pronounced at higher tube voltages. |
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Authors:
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Sebastian T Schindera; Isabelle Tock; Daniele Marin; Rendon C Nelson; Rainer Raupach; Marc Hagemeister; Gabriel von Allmen; Peter Vock; Zsolt Szucs-Farkas |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Radiology Volume: 256 ISSN: 1527-1315 ISO Abbreviation: Radiology Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-07-26 Completed Date: 2010-09-24 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0401260 Medline TA: Radiology Country: United States |
Other Details:
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Languages: eng Pagination: 528-35 Citation Subset: AIM; IM |
Affiliation:
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Institute of Diagnostic, Interventional and Pediatric Radiology, University Hospital Berne, University of Berne, Freiburgstrasse 10, CH-3010 Berne, Switzerland. sschindera@aol.com |
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Angiography / instrumentation, methods* Aortic Aneurysm / physiopathology*, radiography* Aortography / methods* Body Size* Female Humans Male Middle Aged Phantoms, Imaging Radiographic Image Enhancement / methods* Radiography, Abdominal / methods Radiography, Thoracic / methods Reproducibility of Results Sensitivity and Specificity Thorax / physiopathology Tomography, X-Ray Computed / instrumentation, methods* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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