Document Detail

Effect of air pollution on blood pressure, blood lipids, and blood sugar: a population-based approach.
MedLine Citation:
PMID:  20190657     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To investigate changes in blood pressure, lipids, and sugar associated with changes in exposure to ambient air pollution. METHODS: We conducted secondary analyses of blood pressure and biochemistry markers from Taiwanese Survey on Prevalence of Hyperglycemia, Hyperlipidemia, and Hypertension and air pollution monitoring data in 2002 by applying generalized additive models. RESULTS: We observed increased particulate matter with aerodynamic diameters <10 microm was associated with elevated systolic blood pressure (an interquartile range, 34 microg/m, for 0.47 mmHg; 95% CI, -0.09 to 1.02), triglyceride, apolipoprotein B, hemoglobin A1c, and reduced high-density lipoprotein cholesterol. Elevated ozone was associated with increased diastolic blood pressure, apolipoprotein B, and hemoglobin A1c. CONCLUSIONS: Alterations of atherosclerotic indicators are associated with particulate matter with aerodynamic diameters <10 microm and ozone changes. This might provide a link between air pollution and progression of atherosclerotic cardiovascular diseases.
Kai-Jen Chuang; Yuan-Horng Yan; Tsun-Jen Cheng
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of occupational and environmental medicine / American College of Occupational and Environmental Medicine     Volume:  52     ISSN:  1536-5948     ISO Abbreviation:  J. Occup. Environ. Med.     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-03-10     Completed Date:  2010-06-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9504688     Medline TA:  J Occup Environ Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  258-62     Citation Subset:  IM    
Institute of Occupational Medicine and Industrial Hygiene, College of Public Health, National Taiwan University, Taipei, Taiwan.
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MeSH Terms
Aged, 80 and over
Air Pollutants / adverse effects*
Blood Glucose / metabolism*
Blood Pressure / drug effects*
Environmental Monitoring*
Hemoglobin A, Glycosylated / analogs & derivatives*,  metabolism
Lipids / blood*
Middle Aged
Ozone / adverse effects
Particulate Matter / adverse effects
Regression Analysis
Young Adult
Reg. No./Substance:
0/Air Pollutants; 0/Blood Glucose; 0/Hemoglobin A, Glycosylated; 0/Lipids; 0/Particulate Matter; 0/glucosylated hemoglobin A; 10028-15-6/Ozone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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