| Effect of ACTH administration on the haemodynamic response to arginine-vasopressin in sheep. | |
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MedLine Citation:
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PMID: 6256106 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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1. Blood pressure, heart rate and cardiac output were studies in intace conscious sheep during AVP infusion at 0.1, 0.25, 0.5 and 1.0 microgram/min for 30 minutes to determine whether pressor responsiveness to AVP was altered in ACTH-induced hypertension. 2. Prior to ACTH treatment, AVP produced rises in blood pressure associated with a fall in heart rate and cardiac output. 3. During ACTH treatment, pressor responsiveness to AVP and decrease in cardiac output were unchanged, but reflex bradycardia was reduced. 4. ACTH-induced hypertension in sheep is not associated with enhanced pressor responsiveness to AVP. |
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Authors:
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J P Coghlan; D A Denton; W F Graham; T J Humphrey; R T Mason; E G Schnieder; B A Scoggins; J A Whitworth |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Clinical and experimental pharmacology & physiology Volume: 7 ISSN: 0305-1870 ISO Abbreviation: Clin. Exp. Pharmacol. Physiol. Publication Date: 1980 Sep-Oct |
Date Detail:
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Created Date: 1981-03-17 Completed Date: 1981-03-17 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0425076 Medline TA: Clin Exp Pharmacol Physiol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 559-62 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenocorticotropic Hormone
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pharmacology* Animals Arginine Vasopressin / pharmacology* Blood Pressure / drug effects Cardiac Output / drug effects Heart Rate / drug effects Hemodynamics / drug effects* Hypertension / chemically induced Pressoreceptors / drug effects Reflex / drug effects Sheep |
| Chemical | |
Reg. No./Substance:
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113-79-1/Arginine Vasopressin; 9002-60-2/Adrenocorticotropic Hormone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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