| Effect of a 20-day ski trek on fuel selection during prolonged exercise at low workload with ingestion of 13C-glucose. | |
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MedLine Citation:
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PMID: 19159946 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Fuel selection was measured in five subjects (36.0 +/- 10.5 years old; 87.3 +/- 12.5 kg; mean +/- SD) during a 120-min tethered walking with ski poles (1.12 l O(2) min(-1)) with ingestion of (13)C-glucose (1.5 g kg(-1)), before and after a 20-day 415-km ski trek [physical activity level (PAL) approximately 3], using respiratory calorimetry, urea excretion, and (13)C/(12)C in expired CO(2) and in plasma glucose. Before the ski trek, protein oxidation contributed 9.7 +/- 1.6% to the energy yield (%En) while fat and carbohydrate (CHO) oxidation provided 73.5 +/- 5.5 and 16.7 +/- 6.5%En. Plasma glucose was the main source of CHO (52.9 +/- 9.5%En) with similar contributions from exogenous glucose (27.2 +/- 3.1%En), glucose from the liver (25.6 +/- 8.3%En) and muscle glycogen (20.9 +/- 4.0%En). Endogenous CHO contributed 46.6 +/- 3.9%En. Following the ski trek %En from protein, fat, CHO, exogenous glucose and endogenous CHO were not significantly modified (10.1 +/- 1.3, 15.8 +/- 6.7, 74.1 +/- 6.5, 28.7 +/- 3.0 and 45.5 +/- 7.5%En, respectively) but the %En from plasma glucose and glucose from the liver (41.1 +/- 3.6 and 12.4 +/- 4.0%En) were reduced, while that from muscle glycogen increased (33.0 +/- 4.5%En). These results show that in subjects in the fed state with glucose ingestion during exercise, CHO is the main substrate oxidized, with major contributions from both exogenous and endogenous CHO. Following a ~3-week period of prolonged low intensity exercise, the %En from protein, fat, CHO, exogenous glucose and endogenous CHO were not modified. However, the %En from glucose released from the liver was reduced (possibly due to an increased insulin sensitivity of the liver) while that from muscle glycogen was increased. |
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Authors:
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F Péronnet; M Abdelaoui; C Lavoie; C Marrao; S Kerr; D Massicotte; G Giesbrecht |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't Date: 2009-01-22 |
Journal Detail:
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Title: European journal of applied physiology Volume: 106 ISSN: 1439-6327 ISO Abbreviation: Eur. J. Appl. Physiol. Publication Date: 2009 May |
Date Detail:
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Created Date: 2009-04-22 Completed Date: 2009-07-23 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100954790 Medline TA: Eur J Appl Physiol Country: Germany |
Other Details:
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Languages: eng Pagination: 41-9 Citation Subset: IM |
Affiliation:
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Département de kinésiologie, Université de Montréal, Centre Ville, Montreal, QC, Canada. francois.peronnet@umontreal.ca |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Blood Glucose / metabolism Carbon Dioxide / metabolism Carbon Isotopes / administration & dosage, metabolism, pharmacology Eating / physiology Energy Metabolism / drug effects, physiology Exercise / physiology* Food Preferences / drug effects, physiology* Glucose / administration & dosage, metabolism*, pharmacology Humans Male Oxidation-Reduction Physical Endurance / drug effects, physiology Skiing / physiology* Time Factors Workload* |
| Chemical | |
Reg. No./Substance:
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0/Blood Glucose; 0/Carbon Isotopes; 124-38-9/Carbon Dioxide; 50-99-7/Glucose |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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