| Effect of 0.5% apraclonidine on ptosis in Horner syndrome. | |
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MedLine Citation:
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PMID: 16418668 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To demonstrate the effect of apraclonidine on anisocoria and ptosis in Horner syndrome, one drop of 0.5% apraclonidine was instilled in both eyes of 3 patients who presented with acute Horner syndrome, and the effect on ptosis and anisocoria was documented. As reported in the literature, one drop of 0.5% apraclonidine reverses the anisocoria of Horner syndrome. In addition, 0.5% apraclonidine leads to a complete resolution of the ptosis associated with Horner syndrome, a finding reported once in the literature. Apraclonidine is a safe and readily available alternative to cocaine for the diagnosis of Horner syndrome. |
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Authors:
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Daniel C Garibaldi; Holly B Hindman; Michael P Grant; Nicholas T Iliff; Shannath L Merbs |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Ophthalmic plastic and reconstructive surgery Volume: 22 ISSN: 0740-9303 ISO Abbreviation: Ophthal Plast Reconstr Surg Publication Date: 2006 Jan-Feb |
Date Detail:
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Created Date: 2006-01-18 Completed Date: 2006-03-28 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8508431 Medline TA: Ophthal Plast Reconstr Surg Country: United States |
Other Details:
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Languages: eng Pagination: 53-5 Citation Subset: IM |
Affiliation:
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Division of Oculoplastics Surgery, Wilmer Eye Institute, Johns Hopkins University, School of Medicine, Baltimore, MD 21287, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenergic alpha-Agonists
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administration & dosage,
therapeutic use* Adult Aged Anisocoria / drug therapy, etiology Blepharoptosis / drug therapy*, etiology Clonidine / administration & dosage, analogs & derivatives*, therapeutic use Dose-Response Relationship, Drug Follow-Up Studies Horner Syndrome / complications* Humans Instillation, Drug Male Middle Aged Ophthalmic Solutions |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic alpha-Agonists; 0/Ophthalmic Solutions; 4205-90-7/Clonidine; 66711-21-5/apraclonidine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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