| The Edwards MIRA heart valve prosthesis: a 2-year study. | |
| | |
MedLine Citation:
|
PMID: 15151649 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: The Edwards MIRA mechanical heart valve is designed to optimize hemodynamics, reduce thrombogenicity, and avoid mechanical failure with a special hinge mechanism. The purpose of the study was to investigate the clinical performance and postoperative hemodynamic results of the first European patients receiving Edwards MIRA mechanical heart valves. METHODS: From March 1998 to March 1999 a total of 54 Edwards MIRA valves model numbers 3600 (aortic, n = 44) and 9600 (mitral, n = 10) were implanted in 52 (36 male, 16 female; mean age 61 +/- 10.1 years) consecutive patients undergoing mechanical valve replacement in a prospective study. Follow-up of the patients including physical examination, ECG, blood tests, and Doppler were performed prior to discharge, at 6 months, at 1 year, and at least 2 years postoperatively. RESULTS: Through October 2001 a total of 172 follow-up examinations were completed (51 patients at discharge, 46 patients at 6 months, 43 patients at 12 months, 32 patients at 2 years or beyond). All patients were in NYHA class I and II at the 6-month and 2+-year follow-up. All the patients stated an improved quality of life. Hospital mortality was 1.9%. There were no complications related to anticoagulation. Mean international normalized ratio at 6 months was 3.2 (range 1.9 to 4.3); lactate dehydrogenase was slightly increased with 264 +/- 103 U/L on average (normal value 80 to 240 U/L). No signs of valvular dysfunction or paravalvular leakage were observed. Mean pressure gradients were related to valve diameter: after mitral valve replacement (size 27, 29, 31 mm: 4.8, 3.2, 2.1 mmHg); after aortic valve replacement (size 19, 21, 23, 25 mm: 12.1, 13.1, 9.3, 8.2 mmHg). CONCLUSIONS: These preliminary data suggest good hemodynamic function and a low rate of valve-related complications of the Edwards-MIRA mechanical prosthesis. |
| | |
Authors:
|
Rudolf Driever; Stefan Fuchs; Markus Meissner; Edgar Schmitz; Herbert O Vetter |
Related Documents
:
|
1873039 - Actuarial survival and other events following valve surgery in octogenarians: compariso... 3339899 - Long-term clinical results after mitral valve replacement with the björk-shiley prosth... 1863149 - Survival and valve failure after aortic valve replacement. 7646179 - Intermediate clinical results after aortic valve replacement with the carpentier-edward... 3653119 - Long-term follow-up in 185 patients after mitral valve replacement with the lillehei-ka... 11767189 - Evaluation of valve-related complications in patients with sorin bicarbon prosthesis: a... 22381279 - Decompressive hemicraniectomy, strokectomy, or both in the treatment of malignant middl... 22580389 - Canadian cost- utility analysis of intravenous immunoglobulin for acute childhood idiop... 21885549 - Streptokinase for malignant pleural effusions: a randomized controlled study. |
Publication Detail:
|
Type: Comparative Study; Journal Article |
Journal Detail:
|
Title: Journal of cardiac surgery Volume: 19 ISSN: 0886-0440 ISO Abbreviation: J Card Surg Publication Date: 2004 May-Jun |
Date Detail:
|
Created Date: 2004-05-20 Completed Date: 2004-11-06 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 8908809 Medline TA: J Card Surg Country: United States |
Other Details:
|
Languages: eng Pagination: 226-31 Citation Subset: IM |
Affiliation:
|
Department of Cardiothoracic Surgery, Heart Center, University of Witten/Herdecke, Wuppertal, Germany. dr.driever@t-online.de |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Aged, 80 and over Aortic Valve / pathology, surgery, ultrasonography Echocardiography Female Follow-Up Studies Germany / epidemiology Heart Valve Diseases / epidemiology, surgery, ultrasonography Heart Valve Prosthesis* Heart Valve Prosthesis Implantation Humans Male Middle Aged Mitral Valve / pathology, surgery, ultrasonography Morbidity Postoperative Complications / etiology, mortality, ultrasonography Prosthesis Design* Survival Analysis Time Factors Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: N-acetylcysteine reduces lung reperfusion injury after deep hypothermia and total circulatory arrest...
Next Document: The role of corticosteroid therapy following surgery for atrial fibrillation.