Document Detail


Editorial: can gluten contribute to irritable bowel syndrome?
MedLine Citation:
PMID:  21378766     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Functional gastrointestinal disorders are the most common gastroenterological problem in our society. Changes in gut function, including pain perception, motility, and intestinal permeability, and low-grade inflammation have been described in patients with irritable bowel syndrome (IBS). The triggering factors for the described immunity and gut functional changes in patients with IBS are not completely understood. Similarly to post-infective IBS, some patients with IBS symptoms exhibit immunological evidence of gluten sensitivity but have no overt intestinal mucosal injury. They have symptoms that meet the diagnostic criteria for IBS and respond symptomatically to exclusion of gluten from the diet. Thus, gluten sensitivity may be involved in the pathogenesis of a subgroup of IBS patients. Unfortunately, there remain many unanswered questions regarding the mechanistic link between gluten sensitivity and functional gastrointestinal symptoms.
Authors:
Elena F Verdu
Related Documents :
2904116 - Opioid responsiveness in patients with neuroleptic-induced akathisia.
3973576 - Cognitive impairment in patients with tardive dyskinesia.
10432796 - Acoustic startle reflex in schizophrenia patients and their first-degree relatives: evi...
652146 - Serum dopamine-beta-hydroxylase in affective disorders.
12828226 - Raising an isolated low hdl-c level: why, how, and when?
15088156 - Csf-methionine is elevated in psychotic patients.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of gastroenterology     Volume:  106     ISSN:  1572-0241     ISO Abbreviation:  Am. J. Gastroenterol.     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-03-07     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0421030     Medline TA:  Am J Gastroenterol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  516-8     Citation Subset:  IM    
Affiliation:
Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, Ontario, Canada.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Editorial: Exercise for NAFLD: does intensity matter?
Next Document:  The 'wired' universe of organic chemistry.