Document Detail


Editorial: Upper GI bleeding-associated mortality: challenges to improving a resistant outcome.
MedLine Citation:
PMID:  20054306     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Although the incidence of peptic ulcer bleeding (PUB) has decreased, mortality has remained constant despite the advances in endoscopic and pharmacological therapies. Recent data indicate that most PUB-linked deaths are not direct sequelae of the bleeding ulcer itself. Instead, mortality derives from multi-organ failure, cardiopulmonary conditions, or terminal malignancy, suggesting that improving treatments for the bleeding ulcer may impact mortality by very little. Recognizing this possibility is paramount for the implementation of strategies that provide supportive care and prevent complications and key-organ failure, as well as treat the ulcer. Identifying non-gastrointestinal (GI) risk factors for poor outcomes and a multidisciplinary approach for high-risk patients should help to affect this hard outcome.
Authors:
Angel Lanas
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Publication Detail:
Type:  Comment; Editorial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The American journal of gastroenterology     Volume:  105     ISSN:  1572-0241     ISO Abbreviation:  Am. J. Gastroenterol.     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2010-01-07     Completed Date:  2010-02-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0421030     Medline TA:  Am J Gastroenterol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  90-2     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Aged
Cause of Death
Comorbidity
Female
Gastroscopy
Hong Kong / epidemiology
Humans
Incidence
Male
Middle Aged
Peptic Ulcer Hemorrhage / mortality*
Risk Factors
Sex Factors
World Health
Comments/Corrections
Comment On:
Am J Gastroenterol. 2010 Jan;105(1):84-9   [PMID:  19755976 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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