| Edge-to-edge repair with mitral annuloplasty for Barlow's disease. | |
| | |
MedLine Citation:
|
PMID: 16181861 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: The purpose of this study was to define the early and midterm results obtained after the use of edge-to-edge repair with mitral annuloplasty in the setting of Barlow's disease. METHODS: Between 1998 and 2004, 41 patients having Barlow's disease had an edge-to-edge repair creating a double-lumen mitral valve orifice in our unit. In 38 patients (93%), an annuloplasty band was also inserted. RESULTS: Preoperatively, all patients had severe mitral regurgitation (MR), 12 were in New York Heart Association (NYHA) class I, 15 in class II, and 14 in class III. One patient died in hospital (2.4%) and 5 experienced complications (12.5%). There were no late deaths. At follow-up, 2 patients had severe MR and underwent valve replacement, 1 exhibited moderate MR, and 5 had mild MR. Kaplan-Meier 5-year survival, freedom from reoperation and recurrent moderate-severe MR was 97.6% +/- 2.4%, 94% +/- 4.4%, and 90.6% +/- 5.1%, respectively. At latest echocardiographic evaluation (mean 35 +/- 12 months) the mean left ventricular end-systolic and end-diastolic diameters, and the mitral valve area decreased (p = 0.0001) compared with baseline. The mean mitral valve gradient increased (p = 0.001) without clinical evidence of mitral stenosis whereas ejection fraction did not change. Currently, 35 patients are in NYHA class I and 5 are in class II. CONCLUSIONS: In the setting of Barlow's disease, use of edge-to-edge repair with mitral annuloplasty is safe and provides lasting restoration of mitral valve competence with measurable hemodynamic and clinical benefits. In our unit, it is the procedure of choice for correction of MR in patients having Barlow's disease. |
| | |
Authors:
|
Mehmet Oc; George Doukas; Christos Alexiou; Bahar Oc; Leon Hadjinikolaou; Andrzej W Sosnowski; Tomasz J Spyt |
Publication Detail:
|
Type: Clinical Trial; Journal Article |
Journal Detail:
|
Title: The Annals of thoracic surgery Volume: 80 ISSN: 1552-6259 ISO Abbreviation: Ann. Thorac. Surg. Publication Date: 2005 Oct |
Date Detail:
|
Created Date: 2005-09-26 Completed Date: 2006-09-19 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 15030100R Medline TA: Ann Thorac Surg Country: Netherlands |
Other Details:
|
Languages: eng Pagination: 1315-8 Citation Subset: AIM; IM |
Affiliation:
|
Department of Cardiac Surgery, Glenfield Hospital, University of Leicester, Leicester, United Kingdom. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Cardiac Surgical Procedures / methods, statistics & numerical data Echocardiography Female Follow-Up Studies Humans Male Middle Aged Mitral Valve Insufficiency / diagnosis, surgery*, ultrasonography Outcome and Process Assessment (Health Care) Reoperation / statistics & numerical data Survival Analysis Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Isolated mitral valve repair in patients with depressed left ventricular function.
Next Document: Rest and exercise performance of the Medtronic Advantage bileaflet valve in the aortic position.