Document Detail

Ectopic pregnancy with undetectable serum and urine beta-hCG levels and detection of beta-hCG in the ectopic trophoblast by immunocytochemical evaluation.
MedLine Citation:
PMID:  7682319     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Ectopic pregnancies associated with negative urine or serum pregnancy test by radioimmunoassay usually demonstrate either nonviable trophoblast or absent production of beta-hCG by the ectopic pregnancy. CASE: We report a patient with intra-abdominal hemorrhage caused by a ruptured ampullary ectopic pregnancy who had undetectable serum and urine beta-hCG levels (less than 5 mIU/mL). Immunoperoxidase staining of the ectopic trophoblastic tissue obtained at surgery revealed both beta-hCG and placental alkaline phosphatase. CONCLUSION: Negative serum and urine pregnancy tests can occur even though beta-hCG produced by the viable ectopic trophoblastic tissue can be demonstrated by immunoperoxidase staining.
M L Maccato; R Estrada; S Faro
Related Documents :
7646609 - Human chorionic gonadotropin supplementation in recurring pregnancy loss: a controlled ...
6869449 - Amniotic fluid human chorionic gonadotropin in late pregnancy: elevated levels in toxem...
7698849 - Induction of spermatogenesis with gonadotrophins in chinese men with hypogonadotrophic ...
12738129 - Gestational trophoblastic tumor after medical abortion.
22738929 - Prevalence, associated risk factors and effects of hypothyroidism in pregnancy: a study...
3542289 - Automated and manual quantitative assays of choriogonadotropin in serum compared.
8113639 - Epidemiology of hypertensive disorders of pregnancy and childbirth: population-based st...
1973769 - Isolation of fetal trophoblast cells from peripheral blood of pregnant women.
626729 - Effect of maternal glucose ingestion on fetal breathing and body movements in late preg...
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  81     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  1993 May 
Date Detail:
Created Date:  1993-05-13     Completed Date:  1993-05-13     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  878-80     Citation Subset:  AIM; IM    
Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Chorionic Gonadotropin / analysis*
Chorionic Gonadotropin, beta Subunit, Human
Gastrointestinal Hemorrhage / etiology
Immunoenzyme Techniques
Peptide Fragments / analysis*
Pregnancy Tests
Pregnancy, Tubal / diagnosis*
Rupture, Spontaneous
Trophoblasts / chemistry*
Reg. No./Substance:
0/Chorionic Gonadotropin; 0/Chorionic Gonadotropin, beta Subunit, Human; 0/Peptide Fragments

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Pregnancy associated with primary hepatocellular carcinoma.
Next Document:  Persistence of gestational trophoblastic disease for longer than 1 year following evacuation of hyda...