Document Detail


Ectopic pregnancy. A recent five-year study and review of the last 50 years' literature.
MedLine Citation:
PMID:  8913974     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To compare the past and current clinical and pathologic factors that are responsible for ectopic pregnancy (EP). STUDY DESIGN: We performed a retrospective chart and histopathologic specimen review of 740 cases of EP during a recent, five-year period. Products of conception, as well as 240 cases of concomitant endometrial biopsies, were examined. RESULTS: The mean age at presentation, proportion of patients with a history of pelvic inflammatory disease, voluntary interruption of pregnancy (VIP), previous surgery and laterality (right side) of the tubal EP were similar to rates reported in previous studies. Ninety-four percent of the EPs were tubal, and 90% of the tubes exhibited some pathologic changes, including chronic salpingitis (49.5%) and follicular salpingitis (10%), among others. Gestational endometrial patterns were seen in 44% of cases. The corpus luteum of pregnancy was contralateral in 30% of cases in which an ovarian biopsy was performed. CONCLUSION: The factors classically associated with EP remained similar over a period of about 50 years, although the association with VIP still appears to be controversial. Endometrial curettage alone cannot be used to exclude an EP. Ovum transmigration may play a role in the genesis of EP.
Authors:
N C Ramirez; W D Lawrence; K A Ginsburg
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Publication Detail:
Type:  Comparative Study; Journal Article; Review    
Journal Detail:
Title:  The Journal of reproductive medicine     Volume:  41     ISSN:  0024-7758     ISO Abbreviation:  J Reprod Med     Publication Date:  1996 Oct 
Date Detail:
Created Date:  1997-02-20     Completed Date:  1997-02-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0173343     Medline TA:  J Reprod Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  733-40     Citation Subset:  IM    
Affiliation:
Department of Pathology, Hutzel Hospital-Detroit Medical Center, Wayne State University School of Medicine, Michigan, USA.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Biopsy
Cervix Uteri / pathology
Endometrium / pathology
Fallopian Tubes / pathology
Female
Humans
Incidence
Middle Aged
Pregnancy
Pregnancy, Ectopic / epidemiology,  etiology,  pathology*
Pregnancy, Tubal / pathology
Retrospective Studies
Risk Factors
Salpingitis / pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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