Document Detail

Ectopic pregnancy and chlamydial serology.
MedLine Citation:
PMID:  7907037     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To determine the prevalence of humoral IgG antibodies to Chlamydia trachomatis in women with tubal pregnancies. METHODS: A study was made of 49 women with tubal pregnancies. The control group consisted of 50 pregnant women without any known fertility problems. RESULTS: Compared with the pregnant group of women, a statistically significant higher prevalence of chlamydial IgG antibody titer > or = 64 was observed among the patients with gross abnormalities in the fallopian tube contralateral to the ectopic gestation (P = 0.002). The differences in geometric mean titer (GMT) were also statistically significant (P = 0.0004) between those two groups. The recall frequency of past pelvic inflammatory disease (PID) was increased 5-6-fold in patients with ectopic pregnancy, compared with the intrauterine pregnant women. Twenty-five of 30 patients (83%) with ectopic pregnancy and macroscopic tubal sequelae recalled a history of PID. The prevalence of chlamydial IgG antibody titer > or = 64 among women with a past history of PID was 75.6% (34/45), compared with 44.4% (24/54) among the women without any history of past PID history (P = 0.002). Concerning GMT, the numbers were 27 and 154 among women with and without a past history of PID, respectively (Fig. 2). CONCLUSIONS: These findings suggest that C. trachomatis is a major cause of oviductal damage, which predisposes to ectopic pregnancy.
J O Odland; G Anestad; S Rasmussen; R Lundgren; K Dalaker
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics     Volume:  43     ISSN:  0020-7292     ISO Abbreviation:  Int J Gynaecol Obstet     Publication Date:  1993 Dec 
Date Detail:
Created Date:  1994-04-01     Completed Date:  1994-04-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0210174     Medline TA:  Int J Gynaecol Obstet     Country:  IRELAND    
Other Details:
Languages:  eng     Pagination:  271-5     Citation Subset:  IM    
Department of Obstetrics and Gynecology, University Hospital of Tromsø, Norway.
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MeSH Terms
Antibodies, Bacterial / analysis*
Chlamydia Infections / complications*,  immunology
Chlamydia trachomatis / immunology*
Immunoglobulin G / analysis*
Pelvic Inflammatory Disease / complications
Pregnancy, Ectopic / etiology,  microbiology
Pregnancy, Tubal / etiology,  microbiology*
Reg. No./Substance:
0/Antibodies, Bacterial; 0/Immunoglobulin G

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