Document Detail


Ectopic parathyroid carcinoma presenting with hypercalcemic crisis, ectopic uptake in bone scan and obstruction of superior vena cava.
MedLine Citation:
PMID:  21552035     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
A 28-year-old Chinese man diagnosed with hypercalcemic crisis was referred for Tc-99m sestamibi parathyroid imaging, which revealed a massive sestamibi-avid lesion in right-site of upper mediastinum. Contrast-enhanced CT demonstrated the lesion encroached and obstructed bilateral innominate veins and superior vena cava. Tc-99m methylene diphosphonate (MDP) bone scan and SPECT displayed ectopic uptakes in the lungs and stomach. Preoperative suspicion of parathyroid carcinoma prompted an en bloc surgery, which was confirmed in histopathology. Our case showed that although ectopic parathyroid carcinoma causing hypercalcemic crisis, extraskeletal microcalcifications, and great vessel obstruction is rare, parathyroid imaging and bone scan can help solve these diagnostic challenges.
Authors:
Zhaowei Meng; Dong Li; Yujie Zhang; Peng Zhang; Jian Tan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical nuclear medicine     Volume:  36     ISSN:  1536-0229     ISO Abbreviation:  Clin Nucl Med     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-05-09     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7611109     Medline TA:  Clin Nucl Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  487-90     Citation Subset:  IM    
Affiliation:
From the Departments of *Nuclear Medicine, †Radiology, ‡Pathology, and §Thoracic Surgery, Tianjin Medical University General Hospital, Tianjin, P.R.China, Jian Tan MD, Department of Nuclear Medicine, Tianjin Medical University General Hospital, Tianjin, People's Republic of China.
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