| Ecotoxicities of polyquaterniums and their associated polyelectrolyte-surfactant aggregates (PSA) to Gambusia holbrooki. | |
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MedLine Citation:
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PMID: 18172802 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The toxicity of 11 polyquaterniums used in cosmetic applications, and polydimethyldiallylammonium chloride (poly(DADMAC)) were studied for toxicity of the polyquaternium alone, and of a polyquaternium/anionic surfactant complex as occurs in some cosmetic formulations. The surfactant used in the study was sodium dodecyl sulfate (SDS), which is used in cosmetic formulations under its International Nomenclature of Cosmetic Ingredients (INCI) name Sodium Laurel Sulfate. In fish immobilization studies with Gambusia holbrooki, the EC(50) of the polyquaternium/surfactant complex was found to be the same as or similar to the EC(50) for the polyquaternium alone. The toxicity of the polyquaterniums investigated was similar to the published values for other cationic polyelectrolytes and cationic surfactants, in the range from < 1.0 to 10 mg/L, with the exception of low charge density cellulosic polyquaterniums. The anionic surfactant alone was not toxic to fish in the concentration range tested. Results thus showed the toxicity of the polyquaternium was not mitigated by the presence of the anionic surfactant. |
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Authors:
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Janet L Cumming; Darryl W Hawker; Kerry W Nugent; Heather F Chapman |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering Volume: 43 ISSN: 1093-4529 ISO Abbreviation: J Environ Sci Health A Tox Hazard Subst Environ Eng Publication Date: 2008 Feb |
Date Detail:
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Created Date: 2008-01-03 Completed Date: 2008-04-09 Revised Date: 2009-08-14 |
Medline Journal Info:
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Nlm Unique ID: 9812551 Medline TA: J Environ Sci Health A Tox Hazard Subst Environ Eng Country: United States |
Other Details:
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Languages: eng Pagination: 113-7 Citation Subset: IM |
Affiliation:
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School of Environment, Griffith University, Nathan, Australia. janet.cumming@griffith.edu.au |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cosmetics / chemistry, toxicity Cyprinodontiformes / growth & development* Ecotoxicology* Electrolytes / toxicity* Polymers / toxicity* Quaternary Ammonium Compounds / toxicity* Sodium Dodecyl Sulfate / toxicity Surface-Active Agents / toxicity* |
| Chemical | |
Reg. No./Substance:
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0/Cosmetics; 0/Electrolytes; 0/Polymers; 0/Quaternary Ammonium Compounds; 0/Surface-Active Agents; 151-21-3/Sodium Dodecyl Sulfate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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