| Economic burden of rotavirus disease in children under 5 years in Kazakhstan. | |
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MedLine Citation:
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PMID: 21496473 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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BACKGROUND: We aimed to estimate the societal costs of rotavirus cases among children less than 5 years in Kazakhstan, an upper-middle income country in Central Asia. METHODS: Data on medical, non-medical and indirect costs were collected for 190 patients less than 5 years, hospitalized with severe diarrhea in 2009 in two pediatric hospitals. Data on resource use for moderate and mild diarrhea cases were obtained from published sources. A probabilistic sensitivity analysis was performed to explore uncertainty in cost estimates. RESULTS: Approximately 4,000 severe, 30,700 moderate, and 122,900 mild rotavirus cases were estimated annually in children <5 years old. The mean societal cost of a severe, moderate and mild rotavirus case was estimated at US$ 454, 82, and 21, respectively. The total annual cost of rotavirus disease was $37.53 million or on average $107.36 for a child under 5 years old in Kazakhstan. Ninety-four percent of total costs (35.13 million) are indirect costs (productivity losses) from fatal cases and parents' job absenteeism, while direct medical costs account for 2.04 million (5.4%), and direct non-medical for 0.46 million (1.2%). CONCLUSIONS: Rotavirus-associated diarrhea represents a significant economic burden in Kazakhstan, largely due to indirect costs. The costs of rotavirus infections should be considered when planning further preventive actions, including the introduction of rotavirus vaccination. |
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Authors:
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Renat Latipov; Aynagul Kuatbaeva; Olga Kristiansen; Saltanat Aubakirova; Ulbosin Akhanaeva; Ivar Sønbø Kristiansen; Elmira Flem |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-4-12 |
Journal Detail:
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Title: Vaccine Volume: - ISSN: 1873-2518 ISO Abbreviation: - Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-4-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8406899 Medline TA: Vaccine Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 Elsevier Ltd. All rights reserved. |
Affiliation:
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University of Oslo, Reference Laboratory of Ministry of Health of Republic of Uzbekistan, 7A Muradova str., Tashkent 100190, Uzbekistan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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