Document Detail


Ecological relevance and sensitivity depending on the exposure time for two biomarkers.
MedLine Citation:
PMID:  18000848     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Biomarkers are widely used to assess pesticide stress, but their ecological relevance and exposure time dependent sensitivity is still heavily debated. We studied both aspects in larvae of the damselfly Coenagrion puella, comparing the impact of low doses of atrazine, carbaryl, and endosulfan on two key biomarkers (acetylcholinesterase [AChE] activity and fluctuating asymmetry [FA]) and their relationship with life history traits (mortality, development time, growth rate, and body size). Larvae exposed to the pesticides had, in general, longer development times. Size, growth rate, and mortality were not affected by any of the pesticides. In the long-term exposure, AChE activity was diminished by atrazine treatments and stimulated by carbaryl treatments, and was not affected in the endosulfan treatments. FA decreased with increasing endosulfan concentrations and showed no reaction to atrazine or carbaryl. Overall, short-term exposure tended to overestimate the results of long-term exposure decreasing growth rates and enhancing inhibition of AChE activity in atrazine and carbaryl treatments. In line with its ecological relevance, relationship between biomarkers and life history traits showed that AChE inhibition was positively correlated with mortality, while FA was traded off with size. These results show that caution should be exerted when using these biomarkers to assess pesticide pollution in field situations.
Authors:
Melina Campero; Frans Ollevier; Robby Stoks
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Publication Detail:
Type:  Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Environmental toxicology     Volume:  22     ISSN:  1520-4081     ISO Abbreviation:  Environ. Toxicol.     Publication Date:  2007 Dec 
Date Detail:
Created Date:  2007-11-20     Completed Date:  2008-01-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100885357     Medline TA:  Environ Toxicol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  572-81     Citation Subset:  IM    
Affiliation:
Katholieke Universiteit Leuven (KULeuven), Laboratory of Aquatic Ecology, Charles Deberiotstraat 32, B-3000, Leuven, Belgium. campero@supernet.com.bo
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MeSH Terms
Descriptor/Qualifier:
Acetylcholinesterase / metabolism
Animals
Atrazine / toxicity
Biological Markers
Body Constitution*
Carbaryl / toxicity
Endosulfan / toxicity
Environmental Monitoring / methods
Female
Insects / drug effects*,  physiology
Larva / drug effects,  physiology
Male
Pesticides / toxicity*
Water Pollutants, Chemical / toxicity*
Chemical
Reg. No./Substance:
0/Biological Markers; 0/Pesticides; 0/Water Pollutants, Chemical; 115-29-7/Endosulfan; 1912-24-9/Atrazine; 63-25-2/Carbaryl; EC 3.1.1.7/Acetylcholinesterase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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