| Ecological correlates of motor neuron disease mortality: a hypothesis concerning an epidemiological association with radon gas and gamma exposure. | |
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MedLine Citation:
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PMID: 8965106 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This study investigates variations in motor neuron disease (MND) mortality rates between the counties of England and Wales from 1981 to 1989, and their relationship with gamma-ray dose rates, indoor radon gas concentrations and enhanced general life expectancy. A strong correlation was confirmed between age-adjusted rates of MND mortality and life expectancy. Weaker, but statistically significant, associations were observed between indoor radon gas concentrations, terrestrial gamma radiation and marginal variations in MND mortality. Life expectancy and radon gas concentrations were positively associated with MND mortality rates whilst gamma radiation was negatively associated. The negative correlation of gamma radiation with MND mortality may be understood with reference to its negative effects on overall population life expectancy. Radon gas concentrations seemingly account for a small elevation in MND mortality, amounting to at most 4% of total deaths. Further research is required to investigate this association. |
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Authors:
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S Neilson; I Robinson; F C Rose |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of neurology Volume: 243 ISSN: 0340-5354 ISO Abbreviation: J. Neurol. Publication Date: 1996 Apr |
Date Detail:
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Created Date: 1996-12-04 Completed Date: 1996-12-04 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0423161 Medline TA: J Neurol Country: GERMANY |
Other Details:
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Languages: eng Pagination: 329-36 Citation Subset: IM |
Affiliation:
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John Bevan MND Research Unit, Department of Human Sciences, University of West London, Uxbridge, Middlesex, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Dose-Response Relationship, Drug Female Gamma Rays Humans Male Middle Aged Motor Neuron Disease / epidemiology*, mortality* Radon / toxicity* Sex Factors |
| Chemical | |
Reg. No./Substance:
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10043-92-2/Radon |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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