| EcoRI cleavage site variants of mitochondrial DNA molecules from rats. | |
| | |
MedLine Citation:
|
PMID: 273252 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The mitochondrial DNA (mtDNA) molecules of some rats obtained from the SASCO colony contain six EcoRI-sensitive sites while the mtDNA molecules of other rats obtained from the same source contain only four EcoRI sites. By mapping the positions of the EcoRI sites on the molecules relative to the D-loop it was determined that mtDNA molecules from all rats have four EcoRI sites in common, but all the mtDNA molecules of some rats have two extra EcoRI sites. EcoRI sensitivity of mtDNA molecules was shown to be maternally inherited. Construction of heteroduplex molecules failed to reveal evidence of gross nucleotide sequence changes associated with differences in EcoRI sensitivity. |
| | |
Authors:
|
K Buzzo; D L Fouts; D R Wolstenholme |
Publication Detail:
|
Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
|
Title: Proceedings of the National Academy of Sciences of the United States of America Volume: 75 ISSN: 0027-8424 ISO Abbreviation: Proc. Natl. Acad. Sci. U.S.A. Publication Date: 1978 Feb |
Date Detail:
|
Created Date: 1978-05-08 Completed Date: 1978-05-08 Revised Date: 2009-11-18 |
Medline Journal Info:
|
Nlm Unique ID: 7505876 Medline TA: Proc Natl Acad Sci U S A Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 909-13 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Base Sequence Binding Sites DNA Restriction Enzymes* DNA, Mitochondrial* Female Male Rats |
| Chemical | |
Reg. No./Substance:
|
0/DNA, Mitochondrial; EC 3.1.21.-/DNA Restriction Enzymes |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Growth and maintenance of HeLa cells in serum-free medium supplemented with hormones.
Next Document: Theoretical study of genetic variability, assuming stepwise production of neutral and very slightly ...