Document Detail

Eclamptic encephalopathy: imaging and pathogenetic considerations.
MedLine Citation:
PMID:  9404996     Owner:  NLM     Status:  MEDLINE    
Eclampsia is a rare condition peculiar to pregnant and puerperal women, characterized by clinical pre-eclampsia (hypertension, proteinuria, edema) and generalized seizures. Three cases of eclamptic encephalopathy are reported: CT and MRI demonstrated transient abnormalities in the cortical and subcortical regions of the posterior areas of the brain - namely, parieto-occipital lobes - associated with occasional involvement of basal ganglia and/or brainstem. Pathogenesis is still unclear. Strict similarity with the pathological findings characterizing hypertensive encephalopathy suggests that a focal impairment in cerebral autoregulation may be the cause of vasodilation and fluid extravasation leading to hydrostatic edema; selective involvement of posterior areas could be explained by their lesser degree of adrenergic innervation supporting circulatory autoregulation mechanisms.
M Manfredi; A Beltramello; L G Bongiovanni; A Polo; L Pistoia; N Rizzuto
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta neurologica Scandinavica     Volume:  96     ISSN:  0001-6314     ISO Abbreviation:  Acta Neurol. Scand.     Publication Date:  1997 Nov 
Date Detail:
Created Date:  1998-02-04     Completed Date:  1998-02-04     Revised Date:  2006-08-16    
Medline Journal Info:
Nlm Unique ID:  0370336     Medline TA:  Acta Neurol Scand     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  277-82     Citation Subset:  IM    
Dipartimento di Scienze Neurologiche e della Visione, Universitá di Verona, Italy.
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MeSH Terms
Blood-Brain Barrier / physiology
Brain Edema / diagnosis*,  physiopathology
Cerebral Cortex / blood supply,  physiopathology
Eclampsia / diagnosis*,  physiopathology
Follow-Up Studies
Homeostasis / physiology
Infant, Newborn
Magnetic Resonance Imaging
Tomography, X-Ray Computed
Vasodilation / physiology

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