Document Detail

Echocardiography: pericardial tickening and constrictive pericarditis.
MedLine Citation:
PMID:  99019     Owner:  NLM     Status:  MEDLINE    
To evaluate the relation between mitral valve motion and left ventricular end-diastolic pressure, the PR-AC interval, an index derived from the electrocardiogram and mitral echogram, and the left ventricular endodiastolic pressure were determined simultaneously in 22 patients undergoing diagnostic cardiac catheterization. Intravenous infusion of dextran or administration of nitroglycerin was used to alter left ventricular end-diastolic pressure to determine if there was a predictive relation between this pressure and the PR-AC interval during acute hemodynamic manipulations. There was a weak negative correlation (r = -0.33, P less than 0.01) between this pressure and the PR-AC interval. At rest a PR-AC interval greater than 0.06 second correctly predicted a left ventricular end-diastolic pressure of less than 20 mm Hg in 15 of 16 subjects. However, in four of six subjects with a PR-AC interval of 0.06 second or less, the end-diastolic pressure was less than 20 mm Hg. After interventions that varied left ventricular end-diastolic pressure by a factor of 2, the PR-AC interval changed slightly or not at all. These data suggest that the PR-AC interval is of limited value in predicting abnormal values or serial changes in left ventricular end-diastolic pressure.
J R Lewis; J O Parker; G W Burggraf
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of cardiology     Volume:  42     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1978 Sep 
Date Detail:
Created Date:  1978-10-27     Completed Date:  1978-10-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  383-7     Citation Subset:  AIM; IM    
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MeSH Terms
Coronary Disease / physiopathology
Dextrans / diagnostic use
Heart Diseases / physiopathology*
Heart Ventricles / physiopathology*
Middle Aged
Mitral Valve / physiopathology*
Myocardial Contraction
Nitroglycerin / diagnostic use
Pulmonary Valve Stenosis / physiopathology
Reg. No./Substance:
55-63-0/Nitroglycerin; 9004-54-0/Dextrans

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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