Document Detail


Echocardiography in duchenne muscular dystrophy.
MedLine Citation:
PMID:  7412774     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The cardiac function of 36 males with Duchenne muscular dystrophy was evaluated by echocardiography, and the results were compared with the results of other tests of cardiac involvement, including serum creatine kinase isoenzyme evaluation, electrocardiography, chest x-ray, and physical examination of the heart and lungs. Although correlation between the various methods of assessment was not impressive, the echocardiographic technique appeared to be useful in evaluating and following the cardiomyopathy in these patients. Several aspects of left ventricular function were abnormal in most patients, and only two of the 36 had normal left ventricular size and function. Electrocardiographic abnormalities were also apparent in all patients, although the changes were mild in four of the 36. Clinical evaluation, isoenzyme determinations, and chest x-rays have not been useful in assessing cardiac function. The echocardiographic data on these 36 patients are presented in detail and the patients will now be followed sequentially to attempt evaluation of ongoing changes.
Authors:
D Danilowicz; M Rutkowski; D Myung; D Schively
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Muscle & nerve     Volume:  3     ISSN:  0148-639X     ISO Abbreviation:  Muscle Nerve     Publication Date:    1980 Jul-Aug
Date Detail:
Created Date:  1980-11-20     Completed Date:  1980-11-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7803146     Medline TA:  Muscle Nerve     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  298-303     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Child
Child, Preschool
Creatine Kinase / blood
Echocardiography
Electrocardiography
Humans
Isoenzymes
Lung / pathology
Male
Muscular Dystrophies / physiopathology*
Myocardium / pathology
Radiography, Thoracic
Chemical
Reg. No./Substance:
0/Isoenzymes; EC 2.7.3.2/Creatine Kinase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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