Document Detail

Echocardiographic screening to assess the severity of congenital aortic valve stenosis in children.
MedLine Citation:
PMID:  453049     Owner:  NLM     Status:  MEDLINE    
Recent reports suggest that peak left ventricular systolic pressure can be estimated from the echocardiogram. This study compares the accuracy of echocardiographic measurements with clinical estimates of severity of aortic stenosis derived from information of the Joint Natural History Study. Twenty-seven children with isolated aortic valve stensosis were evaluated clinically and with echocardiography and cardiac catheterization. From the echocardiograms, the ratio of systolic left ventricular wall thickness to internal dimension (Ws/Ds) showed a better correlation (r = 0.82) with peak left ventricular systolic pressure than did the diastolic ratio. However, there was significant variation so that a precise estimate of peak left ventricular systolic pressure could not be made from the echocardiogram. Eight of the 27 patients had a normal Ws/Ds ratio (0.55 or less), and their cardiac catheterization data revealed mild aortic stenosis not requiring operation. In contrast, clinical criteria based on the Natural History Study identified only three of the patients with mild aortic stenosis. Prospective studies are needed to confirm the usefulness of echocardiography in noninvasive evaluation of children with aortic valve stenosis.
J L Bass; S Einzig; C Y Hong; J H Moller
Related Documents :
15747039 - Quantification of aortic valve area and left ventricular muscle mass in healthy subject...
9514469 - Comparison of frequency of new coronary events in older persons with mild, moderate, an...
18484159 - Prognostic value of coronary flow reserve and aortic distensibility indices in patients...
21106909 - Myofilament calcium sensitization delays decompensated hypertrophy differently between ...
2956099 - Results of percutaneous catheter valvuloplasty for calcified aortic stenosis in the eld...
15063249 - Role of transvalvular gradient in outcome from valve replacement for aortic stenosis.
7547029 - Percutaneous transluminal coronary angioplasty in patients 70 years of age or older: 12...
22778489 - Growth and remodeling of the left ventricle: a case study of myocardial infarction and ...
6180649 - Cardiovascular and antidepressant effects of imipramine in the treatment of secondary d...
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The American journal of cardiology     Volume:  44     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1979 Jul 
Date Detail:
Created Date:  1979-08-29     Completed Date:  1979-08-29     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  82-7     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Aortic Valve / abnormalities*,  physiopathology
Aortic Valve Stenosis / congenital*,  diagnosis*,  physiopathology
Child, Preschool

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Sensitivity and specificity of MB creatine kinase activity determined with column chromatography.
Next Document:  Left ventricular outflow tract obstruction in transposition of the great arteries: an angiographic s...